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The β-isoform of heat shock protein hsp-90 is structurally related with human microtubule-interacting protein Mip-90
(1999)
Through major research advances in the study of cytoskeletal organization, an integrated view of the complexity of this system has emerged. Recent findings on the microtubule-interacting protein Mip-90, which associates ...
MathFeature: feature extraction package for DNA, RNA and protein sequences based on mathematical descriptors
(2022-01-17)
One of the main challenges in applying machine learning algorithms to biological sequence data is how to numerically represent a sequence in a numeric input vector. Feature extraction techniques capable of extracting ...
Predicting Essential Genes and Proteins Based on Machine Learning and Network Topological Features: A Comprehensive Review
(Frontiers Media Sa, 2016-03-08)
Essential proteins/genes are indispensable to the survival or reproduction of an organism, and the deletion of such essential proteins will result in lethality or infertility. The identification of essential genes is very ...
Systems biology approach predicts antibody signature associated with Brucella melitensis infection in humans
(American Chemical Society, 2011)
A complete understanding of the factors that determine selection of antigens recognized by the humoral immune response following infectious agent challenge is lacking. Here we illustrate a systems biology approach to ...
Structural features of coronavirus SARS-CoV-2 spike protein: Targets for vaccination
Various human pathogenic viruses employ envelope glycoproteins for host cell receptor
recognition and binding, membrane fusion and viral entry. The spike (S) glycoprotein of
betacoronavirus SARS-CoV-2 is a homotrimeric ...
Understanding the role of protein interaction motifs in transcriptional regulators: implications for crop improvement
(Oxford University Press, 2017-05-09)
Recently, the conjunction of disciplines such as developmental biology and proteomics enabled the dissection of diverse cellular processes, by analysis of their transcriptional regulatory pathways. In particular, it has ...
The Development of a Universal In Silico Predictor of Protein-Protein Interactions
(2013-05-31)
Protein-protein interactions (PPIs) are essential for understanding the function of biological systems and have been characterized using a vast array of experimental techniques. These techniques detect only a small proportion ...
The Development of a Universal In Silico Predictor of Protein-Protein Interactions
(2013-05-31)
Protein-protein interactions (PPIs) are essential for understanding the function of biological systems and have been characterized using a vast array of experimental techniques. These techniques detect only a small proportion ...