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Development of an orthotopic model of human metastatic prostate cancer in the NOD‑SCIDγ mouse (Mus musculus) anterior prostate
(2015)
Prostate cancer is one of the most prevalent oncological diseases in males worldwide, and the mortalities resulting from this type of cancer are mainly due to metastasis. The most common models for the study of metastasis ...
Plasma sarcosine measured by gas chromatography-mass spectrometry distinguishes prostatic intraepithelial neoplasia and prostate cancer from benign prostate hyperplasia
(Oxford University Press, 2020)
Objective: Sarcosine was postulated in 2009 as a biomarker for prostate cancer (PCa). Here, we assess plasma sarcosine as a biomarker that is complementary to prostate-specific antigen (PSA).
Methods: Plasma sarcosine ...
Cancer survival in Cali, Colombia : a population-based study, 1995-2004
(2015-02-10)
Background: There is limited information on population-based cancer survival data in Latin America.
Objetive: To obtain estimates of survival for some cancers recognized as a public health priority in Colombia using data ...
Syndecans in the diagnosis and prognosis of prostate cancer Sindecanos: Su potencial uso diagnóstico y pronóstico en cáncer de próstata
(2010)
Syndecans, a family of heparan sulphate proteoglycans that are present in the cell surface are involved in the control of cell proliferation, apoptosis and transformation. Syndecans 1 and 2 have a central role in processes ...
Prostate cancer screening is associated with educational level and knowledge about the disease Nivel educacional como determinante en tamizaje de cáncer de próstata
(Sociedad Medica de Santiago, 2014)
© 2014, Sociedad Medica de Santiago. All rights reserved.Background: The screening of prostate cancer allows an earlier diagnosis, allowing more therapeutic options. This screening depends in part on spontaneous patients’ ...
Molecular signature of cancer stem cells isolated from prostate carcinoma and expression of stem markers in different Gleason grades and metastasis
(2012)
Prostate cancer (PCa) is the most frequently diagnosed malignancy in men worldwide. Chemotherapy response is very poor and resistance to hormone-based treatments is frequent in advances stages. Recently, tumor-initiating ...
Long-acting testosterone injections for treatment of testosterone deficiency after brachytherapy for prostate cancer
(BJU International, 2014)
Objective
To evaluate the clinical and biochemical effects of long-acting
testosterone undecanoate injections in men with prostate
cancer treated with brachytherapy, as the use of testosterone
therapy (TTh) in men with ...
The expression of syndecan-1 and -2 is associated with Gleason score and epithelial-mesenchymal transition markers, E-cadherin and β-catenin, in prostate cancer
(2010)
The epithelial-mesenchymal transition (EMT) is considered a key step in tumor progression, where the invasive cancer cells change from epithelial to mesenchymal phenotype. During this process, a decrease or loss in adhesion ...
Expression of multidrug resistance proteins in prostate cancer is related with cell sensitivity to chemotherapeutic drugs
(2009)
BACKGROUND. Multidrug resistance (MDR) proteins have been associated with the lack of chemotherapy response. Expression of these proteins has been described in the prostate, but there is no information about their role in ...
Morphological Changes of the Cellularity in the Prostatic Gland from Patients with Confirmed Cancer: Gleason Level and Presence of Eosinophils and Mast Cells: Cellular Bioindicators
(Sociedad Chilena de Anatomía Patológica (SCHAP), 2020)
The different pathologies of the prostate, involve the presence of a new microenvironment where inflammatory cells are actively recruited. This research explores the presence of mast cells and eosinophils associated with ...