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Cardiac fibroblast cytokine profiles induced by proinflammatory or profibrotic stimuli promote monocyte recruitment and modulate macrophage M1/M2 balance in vitro
(Academic Press, 2016)
© 2016 Elsevier Ltd Macrophage polarization plays an essential role in cardiac remodeling after injury, evolving from an initial accumulation of proinflammatory M1 macrophages to a greater balance of anti-inflammatory M2 ...
Pro-inflammatory M1 macrophages promote Osteogenesis by mesenchymal stem cells via the COX-2-prostaglandin E2 pathway
(John Wiley and Sons Inc., 2017)
© 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.Bone fractures are among the most common orthopaedic problems that affect individuals of all ages. Immediately after injury, activated macrophages ...
Peptides conjugated to gold nanoparticles induce macrophage activation
Macrophages that react against pathogenic organisms can also be activated with artificial nanometric units consisting of gold nanoparticles (Au NPs) with a peptide coating. Using bone marrow-derived macrophages, here we ...
An in vitro method for studying subcellular rearrangements during cell polarization in Drosophila melanogaster hemocytes
(Elsevier Ireland Ltd, 2018)
© 2018Thanks to the power of Drosophila genetics, this animal model has been a precious tool for scientists to uncover key processes associated to innate immunity. The fly immune system relies on a population of macrophage-like ...
Interleukin-4 Selectively Inhibits Interleukin-2 Secretion by Lipopolysaccharide-Activated Dendritic Cells
Dendritic cells (DCs) generated in vitro from bone marrow precursors using granulocyte-macrophage colony-stimulating factor (GM-CSF) secrete interleukin-2 (IL-2) upon activation, an event probably associated to the ...