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Can pharmacogenetics explain efficacy and safety of cisplatin pharmacotherapy?
(Frontiers Media S.A., 2014)
© 2014 Roco, Cayún, Contreras, Stojanova and Quiñones.Several recent pharmacogenetic studies have investigated the variability in both outcome and toxicity in cisplatin-based therapies. These studies have focused on the ...
Pharmacogenetics research in Brazil: a systematic review.
(Future Medicine, 2022)
Aim: Pharmacogenomics (PGx) is a rising scientific area in many countries, such as Brazil. Objectives: To identify biomarkers, therapeutic areas, probe drugs and regions/ethnicities most studied in the country in order ...
Pharmacogenetics in the treatment of pre-eclampsia: Current findings, challenges and perspectives
(2017-04-01)
Pre-eclampsia (PE) is defined as pregnancy-induced hypertension and proteinuria, and is a major cause of maternal and perinatal morbidity and mortality. A large subgroup of pregnant women with PE is nonresponsive to ...
Cancer pharmacogenetics: Study of genetically determined variations on cancer susceptibility due to xenobiotic exposure Farmacogenética del cáncer: Estudio de variaciones genéticamente determinadas en la susceptibilidad a cáncer por exposición a xenobióti
(2006)
Pharmacogenetics is the study of genetically determined variations in the response to drugs and toxic agents, and their implications on disease. Recently, the discipline has acquired great relevancy due to the development ...
Pharmacogenetics in Psychiatry: Perceived Value and Opinions in a Chilean Sample of Practitioners
(2021)
Use of pharmacogenetics (PGx) testing to guide clinical decisions is growing in developed countries. Published guidelines for gene-drug pair analysis are available for prescriptions in psychiatry, but information on their ...
Pharmacogenetic assessment of tafenoquine efficacy in patients with Plasmodium vivax malaria
(Wolters Kluwer Health, 2020)
Plasmodium vivax has the largest geographic range of human malaria species and is challenging to manage and eradicate due to its ability to establish a dormant liver stage, the hypnozoite, which can reactivate leading to ...
Pharmacogenetics in psychiatry: How far are we from clinical application?Farmacogenética en psiquiatría: ¿qué tan lejos estamos de su aplicación clínica?
(Polemos, 2012-08)
La farmacogenética estudia cómo la variabilidad genética influye en la respuesta de los pacientes a los fármacos. Esta disciplina tendría mayor impacto en la práctica de aquellas especialidades médicas que tratan enfermedades ...
Pharmacogenetics, tobacco, alcohol and its effect on the risk development cancer Farmacogenética, tabaco, alcohol y su efecto sobre el riesgo de desarrollar cáncer
(Sociedad Chilena de Pediatria, 2018)
© 2018, Sociedad Chilena de Pediatria. All rights reserved. Cancer is the second leading cause of death in the world, causing 8.8 million deaths in 2015 according to the World Health Organization (WHO). Risk factors for ...