Now showing items 1-10 of 3748
A review of software tools for pathway crosstalk inference
(Bentham Science Publishers, 2016-11)
Background: We are living in an era that is in general characterized by a lot of data but little information. An enormous amount of biological data collected over several years is now presented as annotations and databases. ...
Crosstalk pathway inference using topological information and biclustering of gene expression data
Detection of crosstalks among pathways is a challenging task, which requires the identification of different types of interactions associated with cellular processes. A common strategy used in bioinformatics consists in ...
Bacterial pathways for the degradation of polychlorinated biphenyls
Polychlorinated biphenyls (PCBs) are one of the most widely distributed chlorinated pollutants in the environment. Bioremedation seems to be a promising approach for the clean-up of PCB-contaminated soils and aquatic ...
Genetic Profiling of the Isoprenoid and Sterol Biosynthesis Pathway Genes of Trypanosoma cruzi
(Public Library of Science, 2014-05)
InTrypanosoma cruzithe isoprenoid and sterol biosynthesis pathways are validated targets for chemotherapeuticintervention. In this work we present a study of the genetic diversity observed in genes from these pathways. ...
Pathway network inference from gene expression data
(BioMed Central, 2014-03)
Background: The development of high-throughput omics technologies enabled genome-wide measurements of the activity of cellular elements and provides the analytical resources for the progress of the Systems Biology discipline. ...
Characterization of the Arabidopsis clb6 Mutant Illustrates the Importance of Posttranscriptional Regulation of the Methyl-D-Erythritol 4-Phosphate Pathway
The biosynthesis of isopentenyl diphosphate and dimethylallyl diphosphate, the two building blocks for isoprenoid biosynthesis, occurs by two independent pathways in plants. The mevalonic pathway operates in the cytoplasm, ...
De novo assembly and functional annotation of Myrciaria dubia fruit transcriptome reveals multiple metabolic pathways for L-ascorbic acid biosynthesis
Background. Myrciaria dubia is an Amazonian fruit shrub that produces numerous bioactive phytochemicals, but is best known by its high L-ascorbic acid (AsA) content in fruits. Pronounced variation in AsA content has been ...
Biosynthetic origins of the isoprene units of gaudichaudianic acid in Piper gaudichaudianum (Piperaceae)
(Elsevier B.V., 2007-08-01)
The biosynthesis of (2S)-2-methyl-2-(4'-methyl-3-pentenyl)-8-(3-methyl-2-butenyl)-2H-1-benzopyran-6-carboxylic acid (gaudichaudianic acid), the major metabolite in leaves and roots of Piper gaudichaudianum Kunth (Piperaceae), ...
Analysis of expression pathways alterations of Arabidopsis thaliana induced by a Necrosis- and Ethylene-inducing protein
(Elsevier Science BvAmsterdamHolanda, 2009)
Urothelial endocytic vesicle recycling and lysosomal degradative pathway regulated by lipid membrane composition
(Springer Verlag Berlín, 2013-02)
The urothelium, a specialized epithelium that covers the mucosa cell surface of the urinary bladder, undergoes dramatic morphological changes during the micturition cycle that involve a membrane apical traffic. This traffic ...