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Superoxide radical and nephrotoxic effect of cadmium exposure
(1999-06-21)
Pollution and industrial practices result in concentrations of metals and other environmental agents that are related to environmental toxicity. Concentrations of metals are widely related to biochemicals values which are ...
Superoxide radical and nephrotoxic effect of cadmium exposure
(1999-06-21)
Pollution and industrial practices result in concentrations of metals and other environmental agents that are related to environmental toxicity. Concentrations of metals are widely related to biochemicals values which are ...
Alteration in cellular viability, pro-inflammatory cytokines and nitric oxide production in nephrotoxicity generation by Amphotericin B: Involvement of PKA pathway signaling
(2013-10-11)
Amphotericin B is one of the most effective antifungal agents; however, its use is often limited owing to adverse effects, especially nephrotoxicity. The purpose of this study was to evaluate the effect of inhibiting the ...
Role of protein kinase A signaling pathway in cyclosporine nephrotoxicity
(Informa Healthcare, 2014-09-01)
Cyclosporine is an important immunosuppressive agent; however, nephrotoxicity is one of the main adverse effects. The purpose of this study was to evaluate the effect of inhibiting the protein kinase A (PKA) signaling ...
Predictive Usefulness of Urinary Biomarkers for the Identification of Cyclosporine A-Induced Nephrotoxicity in a Rat Model
(Public Library Science, 2014-07-29)
The main side effect of cyclosporine A (CsA), a widely used immunosuppressive drug, is nephrotoxicity. Early detection of CsA-induced acute nephrotoxicity is essential for stop or minimize kidney injury, and timely detection ...
The effects of oral glutamine on cisplatin-induced nephrotoxicity in rats
(Elsevier B.V., 2003-06-01)
The antioxidant activity of the amino acid glutamine was investigated to obtain protection against peroxidative damage in rat kidney and nephrotoxicity induced by the treatment with a single dose of the antitumoral cisplatin ...
The effects of oral glutamine on cisplatin-induced nephrotoxicity in rats
(Elsevier B.V., 2003-06-01)
The antioxidant activity of the amino acid glutamine was investigated to obtain protection against peroxidative damage in rat kidney and nephrotoxicity induced by the treatment with a single dose of the antitumoral cisplatin ...
Epigenetic mechanisms involved in cisplatin-induced nephrotoxicity: An update
(MDPI, 2021)
Cisplatin is an antineoplastic drug used for the treatment of many solid tumors. Among its
various side effects, nephrotoxicity is the most detrimental. In recent years, epigenetic regulation
has emerged as a modulatory ...
The effects of oral glutamine on cisplatin-induced nephrotoxicity in rats
(Elsevier B.V., 2014)
l-amino acid oxidase from Bothrops marajoensis causes nephrotoxicity in isolated perfused kidney and cytotoxicity in MDCK renal cells
(Elsevier B. V., 2015-09-15)
Renal alterations caused by Bothrops venom and its compounds are studied to understand these effects and provide the best treatment. Previously, we studied the renal effect of the whole venom of Bothrops marajoensis and ...