Search
Now showing items 1-10 of 81
Balance between early life tolerance and sensitization in allergy: dependence on the timing and intensity of prenatal and postnatal allergen exposure of the mother
(WILEY-BLACKWELL PUBLISHING, INC, 2009)
P>Allergens can be maternally transferred to the fetus or neonate, though it is uncertain how this initial allergen exposure may impact the development of allergy responses. To evaluate the roles of timing and level of ...
Developmental changes in cold tolerance and ability to autoresuscitate from hypothermic respiratory arrest are not linked in rats and hamsters
(Elsevier B.V., 2012-05-31)
In adult mammals, severe hypothermia leads to respiratory and cardiac arrest, followed by death. Neonatal rats and hamsters can survive much lower body temperatures and, upon artificial rewarming, spontaneously recover ...
Effect of neonatal clomipramine treatment on consummatory successive negative contrast
(Universidad de Valencia. Departamento de Metodología de las Ciencias del Comportamiento, 2013-01)
Neonatal administration of clomipramine (CLI) produces physiological, neuroendocrinal and behavioral abnormalities in rats when they reach adulthood, which are similar to those observed in animal models of depression. In ...
CpG-Induced Th1-Type Response in the Downmodulation of Early Development of Allergy and Inhibition of B7 Expression on T Cells of Newborn Mice
(SPRINGER/PLENUM PUBLISHERS, 2010)
Several differences have been described between neonatal and adult immune responses. The predisposition in early life to Th2-type response or tolerance makes it a susceptible period for infections and allergic sensitization. ...
Effect of neonatal treatment with clomipramine on consummatory successive negative contrast
(Universidad de Valencia. Departamento de Metodología de las Ciencias del Comportamiento, 2013-01)
Neonatal administration of clomipramine (CLI) produces physiological, neuroendocrinal and behavioral abnormalities in rats when they reach adulthood, which are similar to those observed in animal models of depression. In ...
Diabetes evolution in rats after neonatal treatment with alloxan
(2005-12-01)
Physical exercises have been recommended in the prevention of non-insulin dependent diabetes mellitus (NIDDM), but the mechanisms involved in this intervention are not yet fully understood. Experimental models offer the ...
Glibenclamide unresponsiveness in a Brazilian child with permanent neonatal diabetes mellitus and DEND syndrome due to a C166Y mutation in KCNJ11 (Kir6.2) gene
(Sociedade Brasileira de Endocrinologia e Metabologia, 2008)
Heterozygous activating mutations of KCNJ11 (Kir6.2) are the most common cause of permanent neonatal diabetes mellitus (PNDM) and several cases have been successfully treated with oral sulfonylureas. We report on the ...
Neonatally Induced Mild Diabetes in Rats and Its Effect on Maternal, Placental, and Fetal Parameters
(Hindawi Publishing Corporation, 2012-01-01)
The aim of this study was to assess placental changes and reproductive outcomes in neonatally induced mild diabetic dams and fetal development in their offspring. At birth, female rats were assigned either to control or ...
Genetic vaccine for tuberculosis (pVAXhsp65) primes neonate mice for a strong immune response at the adult stage
(2007)
Abstract
Background
Vaccination of neonates is generally difficult due to the immaturity of the immune system and consequent ...