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Enhanced immunization techniques to obtain highly specific monoclonal antibodies
(2018-01-02)
Despite fast advances in genomics and proteomics, monoclonal antibodies (mAbs) are still a valuable tool for areas such as the evolution of basic research in stem cells and cancer, for immunophenotyping cell populations, ...
Effects Of STZ Neonatal Administration on Maternal Glucose Tolerance in Different Reproductive States
(Elsevier B.V., 2021-03-01)
Balance between early life tolerance and sensitization in allergy: dependence on the timing and intensity of prenatal and postnatal allergen exposure of the mother
(WILEY-BLACKWELL PUBLISHING, INC, 2009)
P>Allergens can be maternally transferred to the fetus or neonate, though it is uncertain how this initial allergen exposure may impact the development of allergy responses. To evaluate the roles of timing and level of ...
Developmental changes in cold tolerance and ability to autoresuscitate from hypothermic respiratory arrest are not linked in rats and hamsters
(Elsevier B.V., 2012-05-31)
In adult mammals, severe hypothermia leads to respiratory and cardiac arrest, followed by death. Neonatal rats and hamsters can survive much lower body temperatures and, upon artificial rewarming, spontaneously recover ...
Developmental changes in cold tolerance and ability to autoresuscitate from hypothermic respiratory arrest are not linked in rats and hamsters
(Elsevier B.V., 2012-05-31)
In adult mammals, severe hypothermia leads to respiratory and cardiac arrest, followed by death. Neonatal rats and hamsters can survive much lower body temperatures and, upon artificial rewarming, spontaneously recover ...
Adoptive transfer of dendritic cells modulates immunogenesis and tolerogenesis in a neonatal model of murine cutaneous leishmaniasis
(Kinetoplastid Biology and Disease, 2015)
Effect of neonatal clomipramine treatment on consummatory successive negative contrast
(Universidad de Valencia. Departamento de Metodología de las Ciencias del Comportamiento, 2013-01)
Neonatal administration of clomipramine (CLI) produces physiological, neuroendocrinal and behavioral abnormalities in rats when they reach adulthood, which are similar to those observed in animal models of depression. In ...
Papel dos eventos inflamatórios induzidos pela imunização na manutenção de tolerância oral
(Universidade Federal de Minas GeraisUFMG, 2008-02-19)
Oral tolerance is a complex phenomenon defined as a state of systemichyporesponsiveness to an antigen that has been previously administered by the oral route. Many factors affect oral tolerance induction, some of them ...
CpG-Induced Th1-Type Response in the Downmodulation of Early Development of Allergy and Inhibition of B7 Expression on T Cells of Newborn Mice
(SPRINGER/PLENUM PUBLISHERS, 2010)
Several differences have been described between neonatal and adult immune responses. The predisposition in early life to Th2-type response or tolerance makes it a susceptible period for infections and allergic sensitization. ...