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3 SUBTYPES OF ALPHA-BUNGAROTOXIN SENSITIVE NICOTINIC ACETYLCHOLINE-RECEPTORS ARE EXPRESSED IN CHICK RETINA
(Soc Neuroscience, 1993-02-01)
A recent report described the isolation of cDNA clones encoding alpha7 and alpha8 subunits of alpha-bungarotoxin-sensitive nicotinic ACh receptors (alphaBgtAChRs) from chick brain and demonstrated that they were related ...
All you need is coffe
(Fundación Revista Medicina, 2017)
Cholinergic deficit is regarded as an important factor responsible for Alzheimer’s disease symptoms. Two molecular targets for the treatment of this disease are acetylcholinesterase (AChE) and nic otinic receptor (nAChR). ...
Avaliação da expressão gênica e proteica dos receptores nicotínicos em modelo in vitro de infecção por SARS-CoV-2 com e sem superexpressão de ECA2
(Universidade Federal de São Paulo, 2023-02-27)
Introdução: O SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) é o vírus causador da COVID-19 (Coronavírus disease 2019), doença decretada pandêmica em 2020. A entrada do vírus na célula hospedeira ocorre após ...
A conserved arginine with non‐conserved function is a key determinant of agonist selectivity in α7 nicotinic ACh receptors
(Wiley Blackwell Publishing, Inc, 2021-04)
The α7 and α4β2* (“*” denotes possibly assembly with another subunit) nicotinic acetylcholine receptors (nAChRs) are the most abundant nAChRs in the mammalian brain. These receptors are the most targeted nAChRs in drug ...
nAChR-induced octopamine release mediates the effect of nicotine on a startle response in Drosophila melanogaster
(2013)
Biogenic amines (BAs) play a central role in the generation of complex behaviors in vertebrates and invertebrates, including the fly Drosophila melanogaster. The comparative advantages of Drosophila as a genetic model to ...
Activation of single nicotinic receptor channels from Caenorhabditis elegans muscle
(American Society for Pharmacology and Experimental Therapeutics, 2007-05)
Nicotinic acetylcholine receptors (nAChRs) are pentameric neurotransmitter-gated ion channels that mediate synaptic transmission throughout the nervous system in vertebrates and invertebrates. Caenorhabditis elegans is a ...
Mechanism of acetylcholine-induced calcium signaling during neuronal differentiation of P19 embryonal carcinoma cells in vitro
(CHURCHILL LIVINGSTONE, 2008)
Muscarinic (mAChRs) and nicotinic acetylcholine receptors (nAChRs) are involved in various physiological processes, including neuronal development. We provide evidence for expression of functional nicotinic and muscarinic ...