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Randomized crossover study to assess the inter- and intrasubject variability of morning mycophenolic acid concentrations from enteric-coated mycophenolate sodium and mycophenolate mofetil in stable renal transplant recipients
(Wiley-Blackwell, 2010-07-01)
The delayed release of mycophenolic acid (MPA) from enteric-coated mycophenolate sodium (EC-MPS, myfortic (R)) may have an impact on the variability of MPA trough (C(0 h)) levels. A randomized, two-period crossover study ...
In vitro study of antiviral activity of mycophenolic acid on Brazilian orthobunyaviruses
(Karger, 2007-01-01)
Objective: Oropouche, Caraparu, Guama, Guaroa and Tacaiuma are ssRNA viruses that belong to the genus Orthobunyavirus and have been associated with human febrile illnesses and/or encephalitis. In this study, we evaluated ...
In vitro study of antiviral activity of mycophenolic acid on Brazilian orthobunyaviruses
(Karger, 2007-01-01)
Objective: Oropouche, Caraparu, Guama, Guaroa and Tacaiuma are ssRNA viruses that belong to the genus Orthobunyavirus and have been associated with human febrile illnesses and/or encephalitis. In this study, we evaluated ...
Synthesis and immunosuppressive activity of new mycophenolic acid derivatives
(2017-03-01)
Background: Immunosuppressive drugs are widely used to prevent and treat allograft rejection and autoimmune diseases. Mycophenolic acid (MPA) and its derivatives are currently one of the most prescribed immunosuppressive ...
Clinicopathologic features and outcome of mycophenolate-induced colitis in renal transplant recipients
(Wiley-Blackwell, 2014-11-01)
Reports on the clinical course of mycophenolic acid (MPA)-related colitis in kidney transplant recipients are scarce. This study aimed at assessing MPA-related colitis incidence, risk factors, and progression after kidney ...
Diminished Mycophenolic Acid Exposure Caused by Omeprazole May Be Clinically Relevant in the First Week Posttransplantation
(LIPPINCOTT WILLIAMS & WILKINSPHILADELPHIA, 2012)
Background: Some studies have reported a decreased absorption of mycophenolic acid (MPA) from mycophenolate mofetil (MMF) in renal transplanted (RTx) patients under proton-pump inhibitors (PPIs). There is still a lack of ...