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Modulation of the activity of the transverse tubule Mg2+ATPase from frog skeletal muscle by a monoclonal antibody in vitro
(Kluwer Academic Publishers, 1991)
We have established several hybridoma lines that produce monoclonal antibodies against transverse tubule (t-tubule) proteins from frog skeletal muscle. The specificity of these antibodies was characterized by ELISA and ...
Plasma Tau Variants Detected by a Novel Anti-Tau Monoclonal Antibody: A Potential Biomarker for Alzheimer’s Disease
(IOP Publishing, 2020)
Background: A major drawback in Alzheimer's disease (AD) is the lack of validated biomarkers for routine clinical diagnostic. We have reported earlier a novel blood biomarker, named Alz-tau (R), based on variants of platelet ...
Generation of monoclonal antibodies against 17α-hydroxyprogesterone for newborn screening of congenital adrenal hyperplasia
(Elsevier B.V., 2018)
© 2018 Elsevier B.V. Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder caused by the deficiency of one of the five enzymes involved in the biosynthesis of corticosteroids. The most common form of the ...
Hemofilia adquirida tratada con anti-CD20, un anticuerpo anti linfocito B
(SOC MEDICA SANTIAGO, 2011-03)
We report a 54-year-old male presenting with a history or recurrent nose bleeds
and ecchymoses. The coagulation study showed a prolonged partial thromboplastin
time, a factor VIII of 8% and a high inhibitor titer (193 ...
Infliximab en el tratamiento de la enfermedad de Crohn. Estudio preliminar
(2006)
Background: Tumor necrosis factor alpha, interleukin 6 and 1
have a pathogenic role in Crohn’s disease. Infliximab, a monoclonal antibody against tumor
necrosis factor, is useful in the treatment of Crohn’s disease, ...
Eficacia y seguimiento en el largo plazo de pacientes con psoriasis vulgar moderada a severa en tratamiento con infliximab (Remicade®)
(2006)
Background: Psoriasis has a moderate or severe course in 25% of
patients, requiring systemic therapy that is not always successful. Infliximab is a human-murine
monoclonal anti tumor necrosis alpha (TNF- α) antibody. ...
Morphological, immunological and biochemical characterization of purified transverse tubule membranes isolated from rabbit skeletal muscle
(Kluwer Academic Publishers, 1989)
A microsomal fraction consisting of membranes of transverse tubule origin has been purified by a modification of the calcium-loading procedure initially described by Rosemblatt et al. (J Biol Chem 256:8140-8, 1981). Enzymatic ...
Nuevas armas inmunológicas para la medicina del siglo XXI: Terapia biológica basada en el uso de anticuerpos monoclonales de última generación
(Sociedad Médica de Santiago, 2003)
The fusion of a murine B cell and a myeloma cell generates a hybridoma that
produces monoclonal antibody (mAb). These murine mAb induce the HAMA (human anti-mouse
antibodies) response. Murine mAb have been modified by ...
Efficacy of infliximab in patients with moderate and severe psoriasis treated with infliximab (Remicade®) Eficacia y seguimiento en el largo plazo de pacientes con psoriasis búlgara moderada a severa en tratamiento con infliximab (Remicade®)
(2006)
Background: Psoriasis has a moderate or severe course in 25% of patients, requiring systemic therapy that is not always successful. Infliximab is a human-murine monoclonal anti tumor necrosis alpha (TNF- a) antibody. This ...
Epidemiological characteristics of infectious hematopoietic necrosis virus (IHNV): a review
(Biomed Central Ltd., 2016-06-10)
Infectious hematopoietic necrosis virus (IHNV, Rhabdoviridae), is the causative agent of infectious hematopoietic necrosis (IHN), a disease notifiable to the World Organisation for Animal Health, and various countries and ...