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Efeitos dos miRNAs humanos miR-100-5p, miR-192-5p e miR-574-3p na expressão gênica e migração em célula imortalizada de nasofaringe
(Universidade Estadual Paulista (Unesp), 2022-02-21)
Os cânceres são doenças neoplásicas malignas com etiopatogenia complexa. As células transformadas adquirem diversas propriedades que propiciam alterações em taxas de migração, invasão e sobrevivência celular, facilitando ...
Relationship of peripheral blood mononuclear cells miRNA expression and parasitic load in canine visceral Leishmaniasis
(2018-12-01)
Visceral leishmaniasis (VL) in humans is a chronic and often fatal disease if left untreated. Dogs appear to be the main reservoir host for L. infantum infection, however, in many regions other canids such as jackals, ...
Hypoxic Melanoma Cells Deliver microRNAs to Dendritic Cells and Cytotoxic T Lymphocytes through Connexin-43 Channels
(MDPI, 2020)
Alterations in microRNA (miRNA) profiles, induced by tumor microenvironment stressors, like hypoxia, allow cancer cells to acquire immune-resistance phenotypes. Indeed, hypoxia-induced miRNAs have been implicated in cancer ...
Downregulation of exosomal miR-192-5p and miR-204-5p in subjects with nonclassic apparent mineralocorticoid excess.
(2019)
Abstract
Background
The “nonclassic” apparent mineralocorticoid excess (NC-AME) has been identified in approximately 7% of general population. This phenotype is characterized ...
Circulating microRNA signature in non-alcoholic fatty liver disease: from serum non-coding RNAs to liver histology and disease pathogenesis
(B M J Publishing Group, 2014-06)
OBJECTIVES: We used a screening strategy of global serum microRNA (miRNA) profiling, followed by a second stage of independent replication and exploration of liver expression of selected miRNAs to study: (1) the circulating ...
Perfil de expressão dos mIRNAS da família mIR-200 e mIR-192 no rim total e glomérulos isolados de ratos submetidos à restrição protéica in útero
(Universidade Estadual Paulista (Unesp), 2012-07-25)
A desnutrição proteico-calórica representa um problema mundial de saúde pública. O ambiente adverso durante a vida embriofetal e/ou na infância está relacionado com o risco de desenvolver doença na vida adulta. Esse processo ...
Perfil de expressão dos mIRNAS da família mIR-200 e mIR-192 no rim total e glomérulos isolados de ratos submetidos à restrição protéica in útero
(Universidade Estadual Paulista (Unesp), 2012-07-25)
A desnutrição proteico-calórica representa um problema mundial de saúde pública. O ambiente adverso durante a vida embriofetal e/ou na infância está relacionado com o risco de desenvolver doença na vida adulta. Esse processo ...
Gestational low-protein intake enhances whole-kidney MIR-192 and MIR-200 family expression and epithelial-to-mesenchymal transition in rat adult male offspring
(2018-05-01)
Studies have shown that adult offspring of mothers fed a protein-restricted diet during pregnancy present a pronounced reduction of nephron number associated with decreased fractional urinary sodium excretion and arterial ...