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Treatment of rat nephrotoxic nephritis. Use of 5-fluorouracil or methotrexate-5-fluorouracil association
(1984-01-01)
To evaluate the effect of 5-fluorouracil (F) and methotrexate-5-fluorouracil association (MTX-F) on nephrotoxic nephritis, seven groups of 10 rats were inoculated with anti-rat glomerular basement membrane serum (AGBMS); ...
Histological and Histochemical Studies on the Effects of Methotrexate on the Liver of Adult Male Albino Rat
(Sociedad Chilena de Anatomía, 2006)
Análisis del resultado de pruebas hepáticas en pacientes psoriáticos tratados con metotrexato: Estudio retrospectivo
(Sociedad Médica de Santiago, 2007)
Antineoplasic Drug Methotrexate Redox Mechanism Using a Glassy Carbon Electrode
(Wiley-v C H Verlag Gmbh, 2012-04-01)
Methotrexate (MTX) is an antimetabolite of folic acid indicated in the treatment of a variety of cancers. The electrochemical behaviour of MTX on a glassy carbon electrode was investigated. The MTX oxidation is a complex, ...
Effects of methotrexate on the expression of the translational isoforms of glucocorticoid receptors α and β: Correlation with methotrexate efficacy in rheumatoid arthritis patients
(2011)
Objectives: To test the effect of MTX on the expression of glucocorticoid receptor (GR) α and β isoforms AB, C and D in peripheral blood mononuclear cells (PBMCs) in culture, from newly diagnosed RA patients and to evaluate ...
No deleterious effect of low dose methotrexate on titanium implant osseointegration in a rabbit model
(Faculdade de Medicina / USP, 2011)
OBJECTIVE: To evaluate the effect of low dose methotrexate alone or in combination with glucocorticoid treatment on titanium implant osseointegration. METHODS: Groups of 6-8 adult New Zealand White rabbits were treated for ...
Methotrexate delayed wound healing of a pyogenic granuloma in a child with juvenile idiopathic arthritisMetotrexato atrasou a cicatrização de um granuloma piogênico em criança com artrite idiopática juvenile
(2019-10-01)
A nine-year-old girl with of juvenile idiopathic arthritis (JIA) in use of methotrexate complained of a self-bleeding ulcerated lesion exhibiting a red surface in the lower lip. Pyogenic granuloma was confirmed by ...
Synthesis of core@shell nanoparticles functionalized with folic acid-modified PCL-co-PEGMA copolymer for methotrexate delivery
(2021-02-01)
Cancer is responsible for many fatalities and it is considered a public health problem. The side effects caused by conventional treatment are aggressive and painful to patients and can be reduced using nanomaterials that ...
Is the combination of mitomycin C, bleomycin and methotrexate effective as a neoadjuvant treatment for cervical cancer in women?
(I R O G CANADA, INC, 2011)
Objective: To determine the effectiveness of the combination of mitomycin C, bleomycin and methotrexate as a neoadjuvant treatment in preparation for surgical treatment of cervical cancer. Methods and Materials: Twenty-seven ...
Treatment With Methotrexate Inhibits Atherogenesis in Cholesterol-Fed Rabbits
(LIPPINCOTT WILLIAMS & WILKINSPHILADELPHIA, 2012)
A decrease in the number of cardiovascular events in patients with rheumatoid arthritis or psoriasis treated with methotrexate (MTX) has been observed in the literature. The aim of this study was to test whether MTX could ...