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Understanding the antiangiogenic effect of metronomic chemotherapy through a simple mathematical model
(Elsevier B.V., 2016-12-15)
Despite the current and increasingly successful fight against cancer, there are some important questions concerning the efficiency of its treatment in particular, the design of oncology chemotherapy protocols. Seeking ...
Comparative Effectiveness of Two Metronomic Chemotherapy Schedules—Our Experience in the Preclinical Field
(Taylor, 2014-02)
Metronomic chemotherapy refers to the chronic, equally spaced, delivery of low doses of chemotherapeutic drugs, without extended interruptions. Previously, we developed two combined metronomic schemes for the treatment of ...
Metronomic chemotherapy: changing the paradigm that more is better
(Multimed Inc., 2012)
Metronomic chemotherapy in small animal practice: An update
(2016-01-01)
Metronomic chemotherapy can be considered a new chemotherapy modality involving continuous administration of low doses of cytostatic agents which targets endothelial cells. Endothelial cells are vital for the development ...
Toxicity of a methotrexate metronomic schedule in Wistar rats
(2020-10-01)
Metronomic chemotherapy is a relevant strategy that uses low doses of antineoplastic drugs for sustained periods to control tumor growth, an alternative frequently utilized in veterinary patients. This work aimed to evaluate ...
Clinical response in patients with ovarian cancer treated with metronomic chemotherapy
(Cancer Intelligence, 2018)
Therapeutic efficacy of metronomic chemotherapy with cyclophosphamide and doxorubicin on murine mammary adenocarcinomas
(Oxford University Press, 2013-05)
Background: Metronomic chemotherapy (MCT) refers to the chronic and equally spaced administration of low doses of different chemotherapy drugs, without extended rest periods. Herein, we investigated the therapeutic efficacy ...
Achievements and challenges in the use of metronomics for the treatment of breast cancer
(Pergamon-Elsevier Science Ltd, 2020-05)
Two interesting therapeutic proposals for cancer treatment emerged at the beginning of the 21st century. The first one was metronomic chemotherapy, which refers to the chronic administration of chemotherapeutic agents, in ...
Quality of life in patients with metastatic breast cancer treated with metronomic chemotherapy
(Future Medicine, 2016-05)
Aim: The objective of the study was to detect changes in quality of life (QoL) in metastatic breast cancer patients treated with metronomic chemotherapy with daily low doses of cyclophosphamide and celecoxib. Material & ...