Now showing items 1-10 of 1784
Leptin resensitisation: A reversion of leptin-resistant states
Leptin resistance refers to states in which leptin fails to promote its anticipated effects, frequently coexisting with hyperleptinaemia. Leptin resistance is closely associated with obesity and also observed in physiological ...
Effects of diet and bST on expression of leptin and leptin-receptor in mammary parenchyma of heifers
(Amer Dairy Science Assoc-adsa, 2005-01-01)
Central leptin replacement enhances chemorespiratory responses in leptin-deficient mice independent of changes in body weight
Previous studies showed that leptin-deficient (ob/ob) mice develop obesity and impaired ventilatory responses to CO2 . In this study, we examined if leptin replacement improves chemorespiratory responses to hypercapnia (7 ...
Leptin Action In The Thymus.
Facilitation of breathing by leptin effects in the central nervous system
With the global epidemic of obesity, breathing disorders associated with excess body weight have markedly increased. Respiratory dysfunctions caused by obesity were originally attributed to mechanical factors; however, ...
Increased leptin storage with altered leptin secretion from adipocytes of rats with sucrose-induced dyslipidemia and insulin resistance: effect of dietary fish oil
(W B Saunders Co-Elsevier Inc, 2010-06)
This study examined the effect of long-term feeding a high-sucrose diet (SRD) on the modulation of rat adipocyte's leptin secretion and storage. For this purpose, we analyzed (a) basal and insulin-stimulated leptin release ...
Insulin enhances leptin expression in human trophoblastic cells
(Oxford University Press, 2013-06)
Leptin, one of the adipokines that controls energy metabolism via the central nervous system, also has pleiotropic peripheral effects, acting as a proinflammatory cytokine. Leptin is also produced by trophoblastic cells ...
Serum leptin level in hypertensive middle-aged obese women
(Lippincott Williams & Wilkins, 2005-07-01)
The mechanism by which adiposity can raise blood pressure is not fully understood. Leptin has been suggested as a possible cause of the arterial hypertension in obese subjects because leptin induces an increase in sympathetic ...
Control of respiratory and cardiovascular functions by leptin
Leptin, a peptide hormone produced by adipose tissue, acts in brain centers that control critical physiological functions such as metabolism, breathing and cardiovascular regulation. The importance of leptin for respiratory ...