Buscar
Mostrando ítems 1-10 de 30
Localization of EP24.15, a major liver kininase
(Histochemical Soc Inc, 2003-01-01)
The liver is important for the kallikrein-kinin system modulation. This system plays a role in the inflammatory cascade with anticoagulant, profibrinolytic, and anti-adhesive attributes. The metalloendopeptidase EP24.15 ...
Determination of Kininogens Levels and Kallikrein/Kininase II Activities in Patients with Thromboangiitis Obliterans
(WILEY-BLACKWELL, 2010)
Some components of the kinin system such as plasma kallikrein levels, the activities of tissue kallikrein (including saliva) and kininase II and the concentrations of kininogen fractions (low-molecular weight/LKg and ...
Characterization of a kinin inactivating serine endopeptidase H2 (kininase) from human urine using fluorogenic substrates
(Elsevier B.V., 1999-12-01)
We have previously described a kinin-inactivating endopeptidase (H2), which was purified 19-fold from human urine by DEAE-cellulose chromatography and gel filtration. the enzyme was inhibited 100% by PMSF, TPCK and pOHMB. ...
Genetically altered animal models in the kallikrein-kinin system
(Walter de Gruyter & Co, 2006-02-01)
Transgenic and gene-targeting technologies allowing the generation of genetically altered animal models have greatly advanced our understanding of the function of specific genes. This is also true for the kallikrein-kinin ...
Vias metabólicas na degradação da bradicinina e influência de inibidores de cininases
(Universidade Federal de São Paulo (UNIFESP), 1997)
A contribuicao de diferentes atividades cininasicas no metabolismo da bradicinina na circulacao arterial foi avaliada na preparacao de leito vascular mesenterico de rato. Os peptideos bradicinina (BK1-9), BK1-8 e BK1-7 ...
Angiotensin converting-like enzymes from urine of untreated renovascular hypertensive and normal patients: purification and characterization
(Elsevier B.V., 2000-03-01)
Angiotensin converting-like enzymes (ACE) were isolated from urine of normal (P0N, P1N and P2N) and untreated renovascular hypertensive (P-0, P-1 and P-2) patients, the urine were submitted to ion exchange chromatography. ...
Trypanosoma cruzi induces edematogenic responses in mice and invades cardiomyocytes and endothelial cells in vitro by activating distinct kinin receptor subtypes (B-1/B-2)
(Federation Amer Soc Exp Biol, 2002-11-01)
Trypanosoma cruzi, the protozoan that causes Chagas' heart disease, invades endothelial cells in vitro by activating the B-2 kinin receptor (B2R). Here, we demonstrate that mice infected with trypomastigotes develop potent ...
The Kinin System in Patients with Systemic Lupus Erythematosus Exhibiting Mucocutaneous Lesions: A Clinical Study
(WILEY-BLACKWELL PUBLISHING, INC, 2010)
In the present study, we evaluated the kinin system components in the plasma of patients with systemic lupus erythematosus exhibiting mucocutaneous lesions. Fifteen women with active cutaneous lupus (P) and 15 normal healthy ...
Papel do receptor B1 para cininas e o efeito da inibição da enzima conversora de angiotensina em ataques agudos de gota em roedores
(Universidade Federal de Santa MariaBRBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica, 2014-08-20)
Gout, or gouty arthritis, has been associated of a range of comorbidities as hypertension and kidney diseases. Some studies have indicated that certain antihypertensive drugs, such as angiotensin I-converting enzyme ...