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Possible roles of the hereditary hemochromatosis protein, HFE, in regulating cellular iron homeostasis
(Sociedad de Biología de Chile, 2006)
Uncoupling and oxidative stress in liver mitochondria isolated from rats with acute iron overload
(SPRINGER, 2009)
One hypothesis for the etiology of cell damage arising from iron overload is that its excess selectively affects mitochondria. Here we tested the effects of acute iron overload on liver mitochondria isolated from rats ...
Ethnic differences in adverse iron status in early pregnancy: a cross-sectional population-based study
(Cambridge University Press, 2022)
We studied ethnic differences in terms of iron status during pregnancy between Dutch women and other ethnicities and explore to what extent these differences can be explained by environmental factors. This cross-sectional ...
Iron overload induces changes of pancreatic and duodenal divalent metal transporter 1 and prohepcidin expression in mice
(Jena Gustav Fischer Verlag, 2014-06)
It is well known that the iron content of the body is tightly regulated. Iron excess induces adaptive changes that are differentially regulated in each tissue. The pancreas is particularly susceptible to iron-related ...
Urinary iron excretion induced by intravenous infusion of deferoxamine in ß-thalassemia homozygous patients
(Associação Brasileira de Divulgação Científica, 2002-11-01)
The purpose of the present study was to identify noninvasive methods to evaluate the severity of iron overload in transfusion-dependent ß-thalassemia and the efficiency of intensive intravenous therapy as an additional ...
Iron overload-modulated nuclear factor kappa-B activation in human endometrial stromal cells as a mechanism postulated in endometriosis pathogenesis
(Elsevier Inc., 2015)
© 2015 American Society for Reproductive Medicine. Objective To evaluate the effect of iron overload on nuclear factor kappa-B (NF-κB) activation in human endometrial stromal cells (ESCs). Design Experimental study. Setting ...
Iron overload-modulated nuclear factor kappa-B activation in human endometrial stromal cells as a mechanism postulated in endometriosis pathogenesis
(Elsevier, 2015)
Objective: To evaluate the effect of iron overload on nuclear factor kappa-B (NF-kappa B) activation in human endometrial stromal cells (ESCs).
Design: Experimental study.
Setting: University hospital research ...
Iron-induced changes in nitric oxide and superoxide radical generation in rat liver after lindane or thyroid hormone treatment
(2001)
The involvement of cytosolic nitric oxide (NO) and mitochondrial superoxide radical (O2 ·-) production was evaluated as a mechanism triggering liver oxidative stress in lindane (40 mg/kg) or L-3,3′,5-triiodothyronine (T3, ...