Background: Immunosuppressive drugs are widely used to prevent and treat allograft rejection and autoimmune diseases. Mycophenolic acid (MPA) and its derivatives are currently one of the most prescribed immunosuppressive ...

Immunosuppressed renal recipients are at an increased risk of developing cancer. Leukemias are less frequent than other hematopoietic tumours and development of CML after immunosuppression is rare. We describe a 37-year-old ...

A clinical, descriptive study was conducted at the Transplantation Unit of the Gastroenterology Alfa Institute Hospital das Clínicas da Universidade Federal de Minas Gerais - , in order to investigate the clinical, ...

Although many Trypanosoma cruzi (T. cruzi) strains isolated from a wide range of hosts have been characterized, there is a lack of information about biological features from vertically transmitted strains. We describe the ...

The retrovirus are recognized as pathogenic group of virus for domestic animals. The particularitities of these viruses are the necessity of the enzyme transcriptase reversa, for the conversion of the viral RNA in viral ...

Considerando-se que pacientes com Lúpus Eritematoso Sistêmico são submetidos a tratamento com corticosteróides e imunossupressores, podemos concluir que esta condição pode interferir na presença de microrganismos potencialmente ...

Cyclosporin A (CsA) is an immunossupressive agent largely used in the treatment of organ transplant rejection, but nephrotoxicity is the major side effect which limits its use. The pathophysioiogy of this side effect is ...