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Estimates of autozygosity through runs of homozygosity in farmed coho salmon
(MDPI, 2020)
The characterization of runs of homozygosity (ROH), using high-density single nucleotide polymorphisms (SNPs) allows inferences to be made about the past demographic history of animal populations and the genomic ROH has ...
Runs of homozygosity: current knowledge and applications in livestock
(2017-06-01)
This review presents a broader approach to the implementation and study of runs of homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH and their practical implications. ROH are continuous ...
Study of functional variants in homozygous islands in Nelore cattle
(Oxford Univ Press Inc, 2019-12-01)
Homozygosity analysis in autoimmunity affected individuals and multiplex autoimmune disease families
(Longdom Group, 2017-07-07)
Autoimmune diseases (AD) are responsible for a substantial amount of disability and morbidity worldwide. Research generally focuses on a single disease, although autoimmune phenotypes could represent pleiotropic outcomes ...
Prospection of genomic regions divergently selected in racing line of Quarter Horses in relation to cutting line
(Cambridge Univ Press, 2014-11-01)
Selection of Quarter Horses for different purposes has led to the formation of lines, including racing and cutting horses. The objective of this study was to identify genomic regions divergently selected in racing line of ...
Selection signatures in Canchim beef cattle
(2016-05-05)
Background: Recent technological advances in genomics have allowed the genotyping of cattle through single nucleotide polymorphism (SNP) panels. High-density SNP panels possess greater genome coverage and are useful for ...
Prospection of genomic regions divergently selected in cutting line of quarter horses in relation to racing line
(Elsevier B.V., 2015-04-01)
The objective of this study was to identify genomic regions divergently selected in the cutting line of Quarter Horses in relation to the racing line using SNP genotyping arrays and the relative extended haplotype homozygosity ...
Homozygosity for a factor xii mutation in one female and one male patient with hereditary angio-oedema
(Wiley-blackwell, 2016)
Hereditary angio-oedema (HAE) with normal C1 inhibitor is associated with heterozygous mutations in the factor XII gene (FXII-HAE). We report two Brazilian FXII-HAE families segregating the mutation c.983 C>A (p.Thr328Lys). ...