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A high-throughput screening assay for distinguishing nitrile hydratases from nitrilases
(Soc Brasileira Microbiologia, 2015-05-01)
A modified colorimetric high-throughput screen based on pH changes combined with an amidase inhibitor capable of distinguishing between nitrilases and nitrile hydratases. This enzymatic screening is based on a binary ...
A high-throughput screening assay for distinguishing nitrile hydratases from nitrilases
(Soc Brasileira Microbiologia, 2015)
A high-throughput screening assay for distinguishing nitrile hydratases from nitrilases
(Soc Brasileira Microbiologia, 2015)
High throughput selection of novel plant growth regulators: Assessingthe translatability of small bioactive molecules from Arabidopsis tocrops
(Elsevier, 2016)
tPlant growth regulators (PGRs) have become an integral part of agricultural and horticultural practices.Accordingly, there is an increased demand for new and cost-effective products. Nevertheless, the marketis limited by ...
High-throughput cloning, expression and purification of glycoside hydrolases using Ligation-Independent Cloning (LIC)
(ElsevierAmsterdam, 2014-07)
Recent advances in DNA sequencing techniques have led to an explosion in the amount of available genome sequencing data and this provided an inexhaustible source of uncharacterized glycoside hydrolases (GH) to be studied ...
High throughput selection of novel plant growth regulators: Assessing the translatability of small bioactive molecules from Arabidopsis to crops
(Elsevier Ireland Ltd, 2016)
© 2016 Published by Elsevier Ireland Ltd. Plant growth regulators (PGRs) have become an integral part of agricultural and horticultural practices. Accordingly, there is an increased demand for new and cost-effective products. ...
Modern drug discovery technologies: opportunities and challenges in lead discovery
(Bentham ScienceBussum, 2011-12)
The identification of promising hits and the generation of high quality leads are crucial steps in the early stages of drug discovery projects. The definition and assessment of both chemical and biological space have ...
Integração das técnicas de triagem virtual e triagem biológica automatizada em alta escala: oportunidades e desafios em P&D de fármacos
(Sociedade Brasileira de Química - SBQSão Paulo, 2011)
High-throughput screening (HTS) and virtual screening (VS) are useful methods employed in drug discovery, allowing the identification of promising hits for lead optimization. The efficiency of these approaches depends on ...