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Can immunobiotics beneficially modulate hemato-immune responses in immunocompromised hosts?
(Crc Press-taylor & Francis Group, 2013)
In the present chapter, we revised the progress in the influence of immunobiotic LAB on cells involved in the innate and adaptive immune response with special emphasis in the recovery of the lymphopoiesis and myelopoiesis. ...
The Cancer Therapy-Related Clonal Hematopoiesis Driver Gene Ppm1d Promotes Inflammation and Non-Ischemic Heart Failure in Mice
(Lippincott Williams, 2021-09)
Rationale: Cancer therapy can be associated with short- and long-term cardiac dysfunction. Patients with cancer often exhibit therapy-related clonal hematopoiesis (t-CH), an aggressive form of clonal hematopoiesis that can ...
Csrnp1a is necessary for the development of primitive hematopoiesis progenitors in zebrafishPLOS ONEPLOS ONE
(PUBLIC LIBRAY OF SCIENCE, 2016)
TP53-mediated therapy-related clonal hematopoiesis contributes to doxorubicin-induced cardiomyopathy by augmenting a neutrophil-mediated cytotoxic response
(American Society for Clinical Investigation, 2021-07)
Therapy-related clonal hematopoiesis (t-CH) is often observed in cancer survivors. This form of clonal hematopoiesis typically involves somatic mutations in driver genes that encode components of the DNA damage response ...
Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans
(Cell Press, 2020-12)
Reactive aldehydes arise as by-products of metabolism and are normally cleared by multiple families of enzymes. We find that mice lacking two aldehyde detoxifying enzymes, mitochondrial ALDH2 and cytoplasmic ADH5, have ...
Osteoporosis associated with hematological diseasesOsteoporosis asociada a enfermedades hematológicas
(Intituto Tecnológico de Santo Domingo (INTEC), 2021)
GD1a modulates GM-CSF-induced cell proliferation
(Academic Press Ltd - Elsevier Science Ltd, 2011-12)
Gangliosides have been extensively described to be involved in the proliferation and differentiation of various cell types, such including hematopoietic cells. Our previous studies on murine models of stroma-mediated ...