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Lipid droplets: platforms with multiple functions in cancer hallmarks
(Springer Nature, 2020)
Sweetening the hallmarks of cancer: Galectins as multifunctional mediators of tumor progression
(Rockefeller University Press, 2020-02)
Hanahan and Weinberg have proposed 10 organizing principles that enable growth and metastatic dissemination of cancer cells. These distinctive and complementary capabilities, defined as the “hallmarks of cancer,” include ...
Endoplasmic Reticulum Stress and the Hallmarks of Cancer
(2016)
Tumor cells are often exposed to intrinsic and external factors that alter protein homeostasis, thus producing endoplasmic reticulum (ER) stress. To cope with this, cells evoke an adaptive mechanism to restore ER proteostasis ...
Hallmarks of aging: An autophagic perspective
(Frontiers Media S.A., 2019-01)
Autophagy is a major protein turnover pathway by which cellular components are delivered into the lysosomes for degradation and recycling. This intracellular process is able to maintain cellular homeostasis under stress ...
Extracellular Vesicles as Mediators of Cancer Disease and as Nanosystems in Theranostic Applications
(2021)
Cancer remains a leading cause of death worldwide despite decades of intense efforts to
understand the molecular underpinnings of the disease. To date, much of the focus in research has been on the cancer cells themselves ...
Asymmetric cancer hallmarks in breast tumors on different sides of the body
(Public Library of Science, 2016-07)
During the last decades it has been established that breast cancer arises through the accumulation of genetic and epigenetic alterations in different cancer related genes. These alterations confer the tumor oncogenic ...
Endoplasmic Reticulum Stress and the Hallmarks of Cancer
(Cell Press, 2016)
© 2016 Elsevier Inc. Tumor cells are often exposed to intrinsic and external factors that alter protein homeostasis, thus producing endoplasmic reticulum (ER) stress. To cope with this, cells evoke an adaptive mechanism ...