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Presence of ethanol-sensitive and ethanol-insensitive glycine receptors in the ventral tegmental area and prefrontal cortex in mice
(Wiley, 2021)
Background and Purpose: Glycine receptors composed of α1 and β subunits are
primarily found in the spinal cord and brainstem and are potentiated by ethanol
(10–100 mM). However, much less is known about the presence, ...
Manganese poisoning reduces strychnine-insensitive glycine binding sites in the globus pa11idus of the mouse brain
(Universidad del Zulia, 2013)
Mapping the neurosteroid binding sites on glycine receptors
(Pergamon-Elsevier Science Ltd, 2019-09)
Glycine is a major inhibitory neurotransmitter in the CNS, where it modulates both sensory and motor transduction throughout its binding to glycine receptors (GlyRs), pentameric chloride channels that share structural and ...
Organization of Circadian Behavior Relies on Glycinergic Transmission
(Elsevier Science, 2017-04)
The small ventral lateral neurons (sLNvs) constitute a central circadian pacemaker in the Drosophila brain. They organize daily locomotor activity, partly through the release of the neuropeptide pigment-dispersing factor ...
Glycine receptor subtypes and their roles in nociception and chronic pain
(Frontiers Media, 2022)
Disruption of the inhibitory control provided by the glycinergic system is one of the major mechanisms underlying chronic pain. In line with this concept, recent studies have provided robust proof that pharmacological ...
Effects of Interleukin-1β in Glycinergic Transmission at the Central Amygdala
(Frontiers Media S.A., 2021-03)
Interleukin-1β (IL-1β) is an important cytokine that modulates peripheral and central pain sensitization at the spinal level. Among its effects, it increases spinal cord excitability by reducing inhibitory Glycinergic and ...