Now showing items 1-10 of 219
Estudos de medicamentos biosimilares
In Brazil, the registration of new drugs is carried out only when the regulatory agency (Anvisa, acronym in Portuguese) is fully satisfied with the evidence of their quality, efficacy and safety, presented by a pharmaceutical ...
Comparison of impurity profiles of lipiblock® vs. orlistat using HPLC and LC-MS/MS
Comparative HPLC-UV and LC-MS/MS studies of impurity profiles of a reference sample (Xenical®, F. Hoffmann-La Roche Ltd., Switzerland) vs. generic (Lipiblock®, EMS-Sigma Pharma, a generic drug) were carried out with ethanol ...
Generic-branded drug competition and the price for pharmaceuticals in procurement auctions
This paper studies the effects of generic drug’s entry on bidding behavior of drug suppliers in procurement auctions for pharmaceuticals, and the consequences on procurer’s price paid for drugs. Using an unique data set ...
Generic drugs in Brazil: historical overview and legislation
(PAN AMER HEALTH ORGANIZATION, 2010)
The Brazilian generic drugs policy was implemented in 1999 with the aim of stimulating competition in the market, improve the quality of drugs and improve the access of the population to drug treatment. The process of ...
Access to drugs and the situation of the pharmaceutical market in Ecuador [Acceso a medicamentos y situación del mercado farmacéutico en Ecuador]
(PAN AMERICAN HEALTH ORGANIZATION, 2018)
Farmacovigilância no Brasil: A relação entre polimorfismo de fármacos, efetividade e segurança dos medicamentos
In spite of the stated Brazilian policy on medicines that their quality, effectiveness and safety should be ensured at reasonable cost, hospitals in the ANVISA Surveillance Network have been receiving notifications of ...
Switching stable kidney transplant recipients to a generic tacrolimus Is feasible and safe, but it must be monitored
(Hindawi Publishing Corp., 2017)
Background. Tacrolimus is the primary immunosuppressive drug used in kidney transplant patients. Replacing brand name products with generics is a controversial issue that we studied after a Chilean Ministry of Health mandate ...