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Interplay of fibroblasts with anaplastic tumor cells promotes follicular thyroid cancer progression
(Nature Publishing Group, 2019-05)
Thyroid cancer is the most common endocrine malignancy. Anaplastic thyroid cancer is one of the most aggressive thyroid tumors. It is known that activation of oncogenes and/or inactivation of tumor suppressor genes in tumor ...
In vitro infection of human dura-mater fibroblasts with staphylococcus aureus: Colonization and reactive production of IL-1beta
(Maney Publishing, 2015-10)
Objective: Post-operative meningitis, caused mainly by Staphylococcus aureus and Gram-negative rods, is a life-threatening complication after neurosurgery, and its pathogenesis is far from clear. The purpose of this work ...
Cancer-Associated Fibroblasts in the Breast Tumor Microenvironment
(Springer/Plenum Publishers, 2021-01)
Years of investigation have shed light on a theory in which breast tumor epithelial cells are under the effect of the stromal microenvironment. This review aims to discuss recent findings concerning the phenotypic and ...
Fibroblast encapsulation in hybrid silica-collagen hydrogels
(Royal Society of Chemistry, 2010-01)
Silica-collagen scaffolds are synthesized by the simultaneous polymerization of aqueous silicates and self-assembly of protein triple helices in the presence of living human dermal fibroblasts.
Glyphosate-based herbicides with different adjuvants are more potent inhibitors of 3T3-L1 fibroblast proliferation and differentiation to adipocytes than glyphosate alone
(Springer, 2016-05)
Glyphosate-based herbicides are extensively used for weed control all over the world. Thus, it is important to investigate the putative toxic effects of these commercial formulations which contain not only glyphosate but ...
Effect of hexavalent chromium on proliferation and differentiation to adipocytes of 3T3-L1 fibroblasts
(Elsevier, 2014-02)
Heavy metals contamination has become an important risk factor for public health and the environment. Chromium is a frequent industrial contaminant and is also used in orthopaedic joint replacements made from cobalt–chro ...
Triolein reduces MMP-1 upregulation in dermal fibroblasts generated by ROS production in UVB-irradiated keratinocytes
(Elsevier Ireland, 2017-02)
Background: Cytokine production and oxidative stress generated by ultraviolet radiation B (UVB) skin exposure are main factors of skin photoaging. Interleukin-6 (IL-6) produced by irradiated keratinocytes is proposed to ...