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Alterations of hemorheological parameters and tubulin content in erythrocytes from diabetic subjects
(Pergamon-Elsevier Science Ltd, 2016-05)
Treatment of human erythrocytes with high glucose concentrations altered the content and distributions of three tubulin isotypes, with consequent reduction of erythrocyte deformability and osmotic resistance. In erythrocytes ...
In vitro and ex vivo effect of hyaluronic acid on erythrocyte flow properties
(Biomed Central, 2010-12)
Background: Hyaluronic acid (HA) is present in many tissues; its presence in serum may be related to certaininflammatory conditions, tissue damage, sepsis, liver malfunction and some malignancies. In the present work, ...
Effects of detyrosinated tubulin on Na+,K+-ATPase activity and erythrocyte function in hypertensive subjects
(Elsevier Science, 2015-01)
Formation of tubulin/Na+,K+-ATPase (NKA) complex in erythrocytes of hypertensive subjects results in a 50% reduction in NKA activity. We demonstrate here that detyrosinated tubulin, which is increased in hypertensive ...
Human erythrocytes: cytoskeleton and its origin
(Springer, 2020-05)
In the last few years, erythrocytes have emerged as the main determinant of blood rheology. In mammals, these cells are devoid of nuclei and are, therefore, unable to divide. Consequently, all circulating erythrocytes come ...
Simultaneous Determination of Human Erythrocyte Deformability and Adhesion Energy: A Novel Approach Using a Microfluidic Chamber and the “Glass Effect”
(Humana Press, 2020-10)
The simultaneous determination of adhesion and deformability parameters of erythrocytes was carried out through a microfluidic device, which uses an inverted optical microscope with new image acquisition and analysis ...
PMCA activity and membrane tubulin affect deformability of erythrocytes from normal and hypertensive human subjects
(Elsevier Science, 2015-11)
Our previous studies demonstrated formation of a complex between acetylated tubulin and brain plasma membrane Ca2 +-ATPase (PMCA), and the effect of the lipid environment on structure of this complex and on PMCA activity. ...
Alterations of the erythrocyte membrane by in vitro action of Trichinella spiralis muscle larvae
(Cambridge University Press, 2020)