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Pharmaceutical impurities and degradation products: Uses and applications of NMR techniques
(Elsevier, 2014-04)
Current standards and regulations demand the pharmaceutical industry not only to produce highly pure drug substances, but to achieve a thorough understanding of the impurities accompanying their manufactured drug substances ...
Characterization of two new potential impurities of Valsartan obtained under photodegradation stress condition
(Elsevier Science, 2011-08-25)
A photostability study of Valsartan (VAL) is reported. Exposure of the drug to UV-vis radiation (λ> 320 nm) yielded two previously unknown compounds, which were detected by HPLC. Preparative amounts of the new potential ...
Selected aspects of the chemical and biological profile of triclabendazole: A widely used benzimidazole fasciolicidal agent
(Nova Science Publishers, 2019)
Fasciolosis is a very serious parasiticdisease, caused by Fasciola hepaticaand Fasciola gigantica, which isresponsible for heavy economic losses in the production of sheep and cattle inmany countries around the world. In ...
Selected aspects of the Analytical Chemistry of Amlodipine, a widely used long acting Calcium antagonist
(Nova Science Publishers, 2019)
Amlodipine is a poly-substituted 1,4-dihydropyridine with activity as a calcium antagonist. The drug inhibits the transmembrane influx of calcium ions into vascular smooth muscles and cardiac muscles; therefore, it is ...
Development of an enantioselective capillary electrophoretic method for the simultaneous determination of montelukast enantiomeric and diastereoisomeric forms and its main degradation product
(Wiley VCH Verlag, 2016-06)
A stereoselective CD-MEKC system has been developed for the quality control of Montelukast(MK), commercialized as a pure enantiomer. The proposedmethod is the first onethat allows the simultaneous determination ofMK, its ...
Nanoencapsulación y rutas sintéticas para preparar medicamentos usados como tratamientos químicos contra cáncer colorrectal: una descripción general
(Facultad de Ciencias Exactas y NaturalesManizales, Caldas, ColombiaMaestría en Química, 2021)
Single Atoms: A Challenge for Green ChemistryÁtomos individuales: Un reto para la química verdeÁtomos individuais: Um desafio para a química verde
(Universidad Militar Nueva Granada, 2020)