Now showing items 1-10 of 1771
The preclinical discovery and development of opicapone for the treatment of Parkinson’s disease
(Taylor and Francis Ltd, 2020)
Repeated administration of caffeine induces either sensitization or tolerance of locomotor stimulation depending on the environmental context
(Polish Acad Sciences Inst Pharmacology, 2012-01-01)
Caffeine is the psychostimulant substance consumed in greatest quantities in the world. The repeated administration of psychostimulants can either decrease or increase the drug effect, inducing tolerance or sensitization, ...
Imported strongyloidiasis: Epidemiology, presentations, and treatment
Strongyloidiasis is extremely more frequent in immigrants than in travellers. Clinical presentations do not differ significantly between the two groups, and the most frequent picture is a chronic infection characterized ...
Antinociceptive effects of morphine, fentanyl, tramadol and their combination, in morphine-tolerant mice
(Elsevier Inc., 2010)
The development of morphine-tolerance after chronic administration, reduces analgesic efficacy and is a significant clinical problem in some patients; may be managed clinically by increasing the doses of morphine and/or ...
Morfina nasal: Avaliacao da analgesia e dos efeitos colaterais no tratamento da dor pos-operatoria em criancas
Background and Objectives - Postoperative pain is one of the major discomforts but often under treated, especially in the pediatric patient. The aim of this study was to evaluate nasal morphine postoperative analgesia as ...