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The prodrug approach: A successful tool for improving drug solubility
(2016-01-01)
Prodrug design is a widely known molecular modification strategy that aims to optimize the physicochemical and pharmacological properties of drugs to improve their solubility and pharmacokinetic features and decrease their ...
Effect of 70-kDa and 148-kDa dextran hydrogels on praziquantel solubility
(2016-03-01)
Praziquantel is an anthelmintic widely used in the treatment of schistosomiasis. Although a highly permeable drug, praziquantel is poorly soluble in water, limiting its bioavailability. Improving the solubility of poorly ...
Nanotechnology-based drug delivery systems for treatment of hyperproliferative skin diseases - a review
(2013-04-12)
The chronic hyperproliferative diseases (CHD) include cancer, precancerous lesions and diseases of unknown etiology such as psoriasis. Various drugs have been used in the treatment of CHD, such as antiproliferative and ...
Nanotechnology-based drug delivery systems for treatment of hyperproliferative skin diseases - a review
(2013-04-12)
The chronic hyperproliferative diseases (CHD) include cancer, precancerous lesions and diseases of unknown etiology such as psoriasis. Various drugs have been used in the treatment of CHD, such as antiproliferative and ...
Nanonization techniques to overcome poor water-solubility with drugs
(Universidade Federal de Minas GeraisBrasilFAR - DEPARTAMENTO DE ALIMENTOSUFMG, 2020)
Development and characterization of a biocompatible soybean oil-based microemulsion for the delivery of poorly water-soluble drugs
(Wiley-Blackwell, 2015)
The aim of this work was the development and characterization of a biocompatible microemulsion (ME) containing soybean oil (O), phosphatidylcholine/sodium oleate/Eumulgin®HRE40 as the surfactant mixture (S) and water or ...