Now showing items 1-10 of 12991
Estudos sobre liberação controlada e vetorização de drogas através de lipossomas
The text highlights the state of research related with the application of liposomes in the control of drug delivery and drug target to infectious diseases. Liposomes have several pharmaceutical applications and this ...
Neutrophil-Derived MMP-8 Drives AMPK-Dependent Matrix Destruction in Human Pulmonary Tuberculosis
(Public Library of Science, 2015)
Pulmonary cavities, the hallmark of tuberculosis (TB), are characterized by high mycobacterial load and perpetuate the spread of M. tuberculosis. The mechanism of matrix destruction resulting in cavitation is not well ...
Killing of Cryptosporidium sporozoites by Lactoferrin
(American Society of Tropical Medicine and Hygiene, 2017)
Intestinal infection caused by Cryptosporidium is a major contributor to diarrhea morbidity and mortality in young children around the world. Current treatments for children suffering from cryptosporidiosis are suboptimal. ...
Rational use of topical corticosteroids
Many dermatological conditions will respond to a topical corticosteroid. The clinical outcome will depend on making a correct clinical diagnosis and applying the right molecule in the most appropriate vehicle for the correct ...
Liposomes and micro/nanoparticles as colloidal carriers for nasal drug delivery
The use of the nasal route for drug delivery has attracted much interest in recent years in the pharmaceutical field. Local and principally systemic drug delivery can be achieved by this route of administration. But the ...
Sistemas para liberação colônica: Uma alternativa para a veiculação de fármacos para efeito local ou sistêmico
Problems related to the systemic administration of drugs, such as biodistribution, difficulty of targeting, necessity of high doses to achieve adequate levels of the drug in specific sites, toxicity, and undesirable side ...