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Structure-based drug design to overcome drug resistance: challenges and opportunities
(Bentham ScienceBussum, 2014-02)
Drug resistance is a common concern for the development of novel antiviral, antimicrobial and anticancer therapies. To overcome this problem, several strategies have been developed, many of which involving the theme of ...
Advances in prodrug design
(2005-10-01)
The background of prodrug design is presented herein as the basis for introducing new and advanced latent systems, taking into account mainly the versatility of polymers and other macromolecules as carriers. PDEPT ...
Advances in prodrug design
(2005-10-01)
The background of prodrug design is presented herein as the basis for introducing new and advanced latent systems, taking into account mainly the versatility of polymers and other macromolecules as carriers. PDEPT ...
Advances in prodrug design
(2014)
Multi-target pharmacology: Possibilities and limitations of the "skeleton key approach" from a medicinal chemist perspective
(Frontiers Research Foundation, 2015-09)
Multi-target drugs have raised considerable interest in the last decade owing to their advantages in the treatment of complex diseases and health conditions linked to drug resistance issues. Prospective drug repositioning ...
Molecular docking and drug discovery in β-adrenergic receptors
(Bentham Science Publishers B.V., 2017)
Investigación y desarrollo de nuevos medicamentos: de la molécula al fármaco
(Sociedad Médica de Santiago, 2001)
Drug delivery systems: Past, present, and future
(Bentham Science Publ Ltd, 2004-07-01)
Drug delivery systems are essential components of drugs controlled release. In the last decades, several drug delivery technologies have emerged including capsules, liposomes. microparticles, nanoparticles, and polymers. ...
Drug delivery systems: Past, present, and future
(Bentham Science Publ Ltd, 2004-07-01)
Drug delivery systems are essential components of drugs controlled release. In the last decades, several drug delivery technologies have emerged including capsules, liposomes. microparticles, nanoparticles, and polymers. ...
Structure- and ligand-based drug design approaches for neglected tropical diseases
(INT UNION PURE APPLIED CHEMISTRYRES TRIANGLE PK, 2012)
Drug discovery has moved toward more rational strategies based on our increasing understanding of the fundamental principles of protein-ligand interactions. Structure( SBDD) and ligand-based drug design (LBDD) approaches ...