Now showing items 1-5 of 5
A Cyclotide Isolated from Noisettia orchidiflora (Violaceae)
Biologically active cyclotides have been found on some flowering plants species and are involved in the role of the plant protection. As part of studies focusing on peptides from Brazilian plant species, we are reporting ...
Peptídeos cíclicos de biomassa vegetal: características, diversidade, biossíntese e atividades biológicas
(Sociedade Brasileira de Química, 2009-01-01)
Natural peptides are outstanding as the most promising macromolecules in the search for new drugs, especially those of cyclic nature. The higher plants revealed a very peculiar composition of their cyclic peptides, which ...
Inhibition of Breast Cancer Cell Migration by Cyclotides Isolated from Pombalia calceolaria
Two new bracelet cyclotides from roots of Pombalia calceolaria with potential anticancer activity have been characterized in this work. The cyclotides Poca A and B (1 and 2) and the previously known CyO4 (3) were de novo ...
Pinpointing disulfide connectivities in cysteine-rich proteins
A simple MD-based protocol is presented to accurately predict both the sequence and order of disulfide bond formation in proteins containing multiple cysteine residues. It provides a detailed description of their dynamical ...