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Disorder transitions and conformational diversity cooperatively modulate biological function in proteins
(Wiley Blackwell Publishing, Inc, 2016-04)
Structural differences between conformers sustain protein biological function. Here, we studied in a large dataset of 745 intrinsically disordered proteins, how ordered-disordered transitions modulate structural differences ...
DE SITTER TRANSITIVITY, CONFORMAL TRANSFORMATIONS AND CONSERVATION LAWS
(World Scientific Publ Co Pte Ltd, 2014-04-01)
Minkowski spacetime is transitive under ordinary translations, a transformation that do not have matrix representations. The de Sitter spacetime, on the other hand, is transitive under a combination of translations and ...
Electrical conductivity of hydrophobically modified polyelectrolytes in methanol/water solution
(2003)
Measurements of the electrical equivalent conductivity of potassium salts of poly(maleic acid-co-1-olefins), PA-nK(2) with n = 12, 18 has been carried out in methanol-water mixtures in the whole range of composition. The ...
Capturing Transition Paths and Transition States for Conformational Rearrangements in the Ribosome
(Cell Press, 2014-12-16)
To reveal the molecular determinants of biological function, one seeks to characterize the interactions that are formed in conformational and chemical transition states. In other words, what interactions govern the molecule's ...
Conformation analysis of a surface loop that controls active site access in the GH11 xylanase A from Bacillus subtilis
(SPRINGERNEW YORK, 2012)
Xylanases (EC 3.2.1.8 endo-1,4-glycosyl hydrolase) catalyze the hydrolysis of xylan, an abundant hemicellulose of plant cell walls. Access to the catalytic site of GH11 xylanases is regulated by movement of a short ...
ELECTRICAL CONDUCTIVITY OF HYDROPHOBICALLY MODIFIED POLYELECTROLYTES IN METHANOL/WATER SOLUTION
(Sociedad Chilena de Química, 2003)
Hydration-dependent conformational states of hemoglobin. Equilibrium and kinetic behavior
(1990-07-27)
The equilibrium and kinetics of methemoglobin conversion to hemichrome induced by dehydration were investigated by visible absorption spectroscopy. Below about 0.20 g water per g hemoglobin only hemichrome was present in ...
Coarse-grained simulations of heme proteins: Validation and study of large conformational transitions
(American Chemical Society, 2016-07)
Heme proteins are ubiquitous in nature and perform many diverse functions in all kingdoms of life. Many of these functions are related to large-scale conformational transitions and allosteric processes. Sampling of these ...
Application of MCR-ALS to reveal intermediate conformations in the thermally induced α-β transition of poly-L-lysine monitored by FT-IR spectroscopy
(Pergamon-Elsevier Science Ltd, 2017-10)
Temperature-induced conformational transitions of poly-L-lysine were monitored with Fourier-transform infrared (FT-IR) spectroscopy between 10 °C and 70 °C. Chemometric analysis of dynamic IR spectra was performed by ...
Investigation of DMSO-Induced Conformational Transitions in Human Serum Albumin Using Two-Dimensional Raman Optical Activity Spectroscopy
(Wiley-Blackwell, 2014-09-01)
Recent Raman and Raman optical activity (ROA) results have demonstrated that dimethyl sulfoxide (DMSO) induces the selective conversion of alpha-helix motifs into the poly(L-proline) II (PPII) helix conformation in an array ...