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Analytical and Clinical Validation for RT-qPCR Detection of SARS-CoV-2 Without RNA Extraction
(Frontiers Media, 2020)
Background: The recent COVID-19 pandemic has posed an unprecedented challenge to laboratory diagnosis, based on the amplification of SARS-CoV-2 RNA. With global contagion figures exceeding 4 million persons, the shortage ...
Agreements between Industry and Academia on Publication Rights: A Retrospective Study of Protocols and Publications of Randomized Clinical Trials
(Public Library Science, 2016)
Background
Little is known about publication agreements between industry and academic investigators in trial protocols and the consistency of these agreements with corresponding statements in publications. We aimed to ...
Should research ethics triumph over clinical ethics?
(2007)
Evidence-based medicine (EBM) and its main strategy, randomized clinical trials, have had less impact on medical practice than might be expected. Of the various reasons that make practitioners wary of applying research ...
Quality of reporting for randomised clinical trials published in Latin American and Spanish journals: A protocol for a systematic survey of three clinical specialities
(BMJ, 2020)
Introduction Quality of reporting refers to how published articles communicate how the research was done and what was found. Gaps and imprecisions of reporting hamper the assessment of the methodological quality and internal ...
Effects of an optimised approach to home-based respiratory care in individuals with amyotrophic lateral sclerosis: a study protocol for a randomised controlled trial
(BMJ, 2021)
Introduction This study aims to investigate the effects of an optimal home-based respiratory care protocol in individuals with amyotrophic lateral sclerosis (ALS). Methods and analysis This is a randomised, blinded controlled ...
Using a Clinical Protocol for Orthognathic Surgery and Assessing a 3-Dimensional Virtual Approach: Current Therapy
(W B SAUNDERS CO-ELSEVIER INC, 2011-03)
Oral and maxillofacial surgeons who perform orthognathic surgery face major changes in their practices, and these challenges will increase in the near future, because the extraordinary advances in technology applied to our ...
Comparison of effectiveness and sensitivity using two in-office bleaching protocols for a 6% hydrogen peroxide gel in a randomized clinical trial
(Indiana University School of Dentistry, 2017)
Objective: The aim of this blinded and randomized clinical trial was to compare two
application protocols (one 36-minute application vs three 12-minute applications). We then
assessed the effectiveness of the bleaching ...
Clinical pharmacology and therapeutic use of antioxidant vitamins
(2007)
The clinical use of antioxidants has gained considerable interest during the last decade. It was suggested from epidemiological studies that diets high in fruits and vegetables might help decrease the risk of cardiovascular ...