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The role of single-nucleotide polymorphism (SNPs) in toxicity of induction chemotherapy based on cisplatin and paclitaxel in patients with advanced head and neck cancer
(2019-11-01)
Background: Induction chemotherapy in locally-advanced head and neck squamous cell carcinoma (LAHNSCC) patients is potentially associated to serious adverse events. Biomarkers associated with toxicity could tailor its ...
Profile of patients with hematological toxicity grades 3 and 4 and gastrointestinal toxicity of patients undergoing chemotherapy
(Universidade Federal de Santa Maria, 2022)
Fatal gemcitabine-induced pulmonary toxicity in metastatic gallbladder adenocarcinoma
(SPRINGER, 2010)
Gemcitabine is a chemotherapy agent that may cause unpredictable side effects. In this report, we describe a fatal gemcitabine-induced pulmonary toxicity in a patient with gallbladder metastatic adenocarcinoma. A 72-year-old ...
Conflicting objectives in chemotherapy with drug resistance
(Pergamon-elsevier Science LtdOxfordInglaterra, 1997)
OPTIMAL CHEMOTHERAPY - A CASE-STUDY WITH DRUG-RESISTANCE, SATURATION EFFECT, AND TOXICITY
(Oxford Univ Press United KingdomOxfordInglaterra, 1994)
Intra-arterial chemotherapy is more effective than sequential periocular and intravenous chemotherapy as salvage treatment for relapsed retinoblastoma
(Wiley, 2013-05)
BACKGROUND: Treatment of eyes with retinoblastoma failing systemic chemoreduction and external beam radiotherapy is seldom efficacious. This study compares the efficacy and toxicity of intra-arterial ophthalmic artery ...
A case-control study of a combination of single nucleotide polymorphisms and clinical parameters to predict clinically relevant toxicity associated with fluoropyrimidine and platinum-based chemotherapy in gastric cancer
(BMC, 2021)
Background: Fluoropyrimidine plus platinum chemotherapy remains the standard first line treatment for gastric
cancer (GC). Guidelines exist for the clinical interpretation of four DPYD genotypes related to severe ...
Platinum Analogs from a Chemical and Biological Point of View
(2022)
Platinum (Pt) analogues are the most widely used chemotherapeutic agents in oncology, used alone or co-administered with other antineoplastic therapy and/or radiation. Pt-based chemotherapies are prescribed to treat a wide ...
Effectiveness and toxicity of first-line methotrexate chemotherapy in low-risk postmolar gestational trophoblastic neoplasia: The New England Trophoblastic Disease Center experience
(2018-01-01)
Objectives To assess the outcomes and toxicity of first-line methotrexate (MTX) chemotherapy in low-risk postmolar gestational trophoblastic neoplasia (GTN) patients receiving 8-day methotrexate or one-day methotrexate ...
Fatal gemcitabine-induced pulmonary toxicity in metastatic gallbladder adenocarcinoma
(Springer, 2010-02-01)
Gemcitabine is a chemotherapy agent that may cause unpredictable side effects. in this report, we describe a fatal gemcitabine-induced pulmonary toxicity in a patient with gallbladder metastatic adenocarcinoma. A 72-year-old ...