Buscar
Mostrando ítems 1-10 de 192
Diverging mechanisms of activation of chemokine receptors revealed by novel chemokine agonists
(Public Library of Science, 2011)
CXCL8/interleukin-8 is a pro-inflammatory chemokine that triggers pleiotropic responses, including inflammation, angiogenesis, wound healing and tumorigenesis. We engineered the first selective CXCR1 agonists on the basis ...
CXCR3 chemokine receptor contributes to specific CD8+ T cell activation by pDC during infection with intracellular pathogens
(Public Library of Science, 2020)
Blockade of the chemokine receptor CXCR2 ameliorates adjuvant-induced arthritis in rats
(NATURE PUBLISHING GROUP, 2008)
Background and purpose: Chemokine receptors CXCR1 and CXCR2 may mediate influx of neutrophils in models of acute and chronic inflammation. The potential benefits of oral administration of a CXCR1/2 inhibitor, DF 2162, in ...
Seric chemokines and chemokine receptors in eosinophils during acute human schistosomiasis mansoni
(Fundação Oswaldo Cruz, 2015)
Modulation of host antiviral restriction factors by ccr5 and cxcr4 ligands
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2019)
Therapeutic Perspectives of HIV-Associated Chemokine Receptor (CCR5 and CXCR4) Antagonists in Carcinomas
(MDPI, 2023-01)
The interaction between malignant cells and the tumor microenvironment is critical for tumor progression, and the chemokine ligand/receptor axes play a crucial role in this process. The CXCR4/CXCL12 and CCR5/CCL5 axes, ...
Expression of the chemokine receptor CXCR4 on lymphocytes of leprosy patients
(Associação Brasileira de Divulgação Científica, 2014)
Dysregulation of stromal derived factor 1/CXCR4 axis in the megakaryocytic lineage in essential thrombocythemia
(Wiley Blackwell Publishing, Inc, 2009-01)
This study investigated the involvement of chemokines including stromal derived factor 1 (SDF-1), interleukin 8 (IL-8), growth-related oncogene alpha (GRO-a) and their receptors, CXCR4, CXCR2 and CXCR1 in essential ...
Altered Chemokine Receptor Expression in Papillary Thyroid Cancer
(MARY ANN LIEBERT, INC, 2009)
Background: Papillary thyroid cancer (PTC), the most prevalent type of differentiated thyroid carcinoma, displays a strikingly high frequency of lymph node metastasis (LNM). Recent data suggest that chemokines can play an ...