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Physangulidine A, a withanolide from Physalis angulata, perturbs the cell cycle and induces cell death by apoptosis in prostate cancer cells
(American Chemical Society, 2013)
Recently, our group reported the discovery of three new withanolides, physangulidines A–C, from Physalis angulata. In this study, the biological effects of physangulidine A (1), which was the most active and abundant of ...
Production of endoglin-specific heavy chain antibody fragments (VHHs) microarrays for whole-cell SPR imaging
(Elsevier, 2022)
Cell-based Surface Plasmon Resonance imaging (SPRi) with anti-endoglin VHH antibodies microarray on a gold-covered biochip was used to characterize the binding to endoglin expressed on the surface membrane of SC cells. ...
Standardization of a fluorescent-based quantitative adhesion assay to study attachment of Taenia solium oncosphere to epithelial cells in vitro
(Elsevier, 2012)
To fully understand the preliminary stages of Taenia solium oncosphere attachment in the gut, adequate tools and assays are necessary to observe and quantify this event that leads to infection. A fluorescent-based quantitative ...
Plagiochiline A Inhibits Cytokinetic Abscission and Induces Cell Death
(MDPI, 2018)
We previously reported on the isolation and biological activities of plagiochiline A (1), a 2,3-secoaromadendrane-type sesquiterpenoid from the Peruvian medicinal plant, Plagiochila disticha. This compound was found to ...
Image-based Quantification of Direct Cell-to-cell Transmission of Bovine Viral Diarrhea Virus
(Bio-protocol, 2019-08)
Different viruses rely on direct cell-to-cell transmission to propagate infection within the infected host. Measuring this mode of transmission in cultured cells is often complicated by the contribution of cell free viruses ...
Stem CellsCélulas-tronco
(HCPA/FAMED/UFRGS, 2008)
Influence of individual cell motility on the 2D front roughness dynamics of tumour cell colonies
(Springer, 2014-06)
The dynamics of in situ 2D HeLa cell quasi-linear and quasi-radial colony fronts in a standard culture medium is investigated. For quasi-radial colonies, as the cell population increased, a kinetic transition from an ...
Insights into Stem Cell Factor chemotactic guidance of neural crest cells revealed by a real-time directionality-based assay
(Elsevier Gmbh, 2012-05)
The extracellular environment through which neural crest cells (NCCs) translocate and differentiate plays a crucial role in the determination of cell migration and homing. In the trunk, NCC-derived melanocyte precursor ...
Cell-to-cell transmission is the main mechanism supporting bovine viral diarrhea virus spread in cell culture
(American Society for Microbiology, 2019-01)
After initiation of an infective cycle, spread of virus infection can occur fundamentally in two different ways: (i) viral particles can be released into the external environment and diffuse through the extracellular space ...