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Cationic antimicrobial peptides inactivate shiga toxin-encoding bacteriophages
(Frontiers Media S.A., 2018)
Shiga toxin (Stx) is the principal virulence factor during Shiga toxin-producing Escherichia coli (STEC) infections. We have previously reported the inactivation of bacteriophage encoding Stx after treatment with chitosan, ...
Study of the antimicrobial peptide indolicidin and mutants in eukaryotic modelled membrane by molecular dynamics simulations
(TAYLOR & FRANCIS LTD, 2011)
In this work the interaction of the antimicrobial peptide indolicidin (IND) and its mutants CP10A and CP11 with a eukaryotic membrane model was examined by molecular dynamics simulations. The aim was to analyse the behaviour ...
Antimicrobial activity of de novo designed cationic peptides against multi-resistant clinical isolates
(Elsevier Masson, 2013-11)
Antibiotic resistance is one of the main problems concerning public health or clinical practice. Antimicrobial peptides appear as good candidates for the development of new therapeutic drugs. In this study we de novo ...
The dynamic action mechanism of small cationic antimicrobial peptides
(Royal Society Of Chemistry, 2014-09)
Antimicrobial peptides form part of the immune system as protection against the action of external pathogens. The differences that exist between mammalian and microbial cell membrane architectures<br />are key aspects of ...
Antitumor effects of cationic synthetic peptides derived from Lys49 phospholipase A2 homologues of snake venoms
(2007)
The effects of two cationic synthetic peptides, derived from the C-terminal region of Lys49 phospholipase A2 homologues from snake
venoms, upon various murine tumor cell lines (B16 melanoma, EMT6 mammary carcinoma, S-180 ...
Antitumor effects of cationic synthetic peptides derived from Lys49 phospholipase A2 homologues of snake venoms
(2007)
The effects of two cationic synthetic peptides, derived from the C-terminal region of Lys49 phospholipase A2 homologues from snake
venoms, upon various murine tumor cell lines (B16 melanoma, EMT6 mammary carcinoma, S-180 ...
Cationic Antimicrobial Peptides Inactivate Shiga Toxin-Encoding Bacteriophages
(Frontiers Research Foundation, 2017-12)
Shiga toxin (Stx) is the principal virulence factor during Shiga toxin-producing Escherichia coli (STEC) infections. We have previously reported the inactivation of bacteriophage encoding Stx after treatment with chitosan, ...
Chemical and Biological Characteristics of Antimicrobial alpha-Helical Peptides Found in Solitary Wasp Venoms and Their Interactions with Model Membranes
(Mdpi, 2019-10-01)
Solitary wasps use their stinging venoms for paralyzing insect or spider prey and feeding them to their larvae. We have surveyed bioactive substances in solitary wasp venoms, and found antimicrobial peptides together with ...
Small Cationic Peptides: Influence of Charge on Their Antimicrobial Activity
(American Chemical Society, 2018-05)
The first stage of the action mechanism of small cationic peptides with antimicrobial activity is ruled by electrostatic interactions between the peptide and the pathogen cell membrane. Thus, an increase in its activity ...
Effect of analogues of cationic peptides on dentin mineralization markers in odontoblast-like cells
(2019-07-01)
Objectives: To evaluate the effect of analogues of cationic peptides on the viability and the expression of phenotypic and genotypic markers of dentin mineralization in MDPC-23 odontoblast-like cells. Materials and methods: ...