Malaria is a disease caused by Plasmodium spp. parasites which affects millions of people every year. Exacerbated immune response by the host triggers a large production of inflammatory cytokines such as IL-1β and TNFα, ...

Background. Apoptosis is a genetically programmed form of cell death, of which caspases are the central components. Methods. By tissue microarray of 229 cases of oral squamous cell carcinoma (OSCC), we analyzed the ...

Malaria is an infectious disease caused by the parasite Plasmodium, which is transmitted through a bite from infected Anopheles mosquitoes. The main features of malaria disease are high parasitemia and systemic production ...

The pathogenic mechanism(s) underlying neurodegenerative diseases associated with protein misfolding is unclear. Several studies have implicated ER stress pathways in neurodegenerative conditions, including prion disease, ...

Studies were designed to examine the expression and activity of four caspases that contribute to the initial (caspases-2, -8, and -9) and final (caspase-3) events in apoptosis in the rat corpus luteum (CL) during pregnancy ...

Apoptosis and necrosis are two distinct forms of cell death that can occur in response to different agents and stress conditions. In order to verify if the oxidative stress induced by dietary selenium and vitamin E ...

Melanoma is an extremely aggressive neoplasm, although it’s morbidity is not so significant among skin cancers. It has a high mortality rate in both human and veterinary medicine. In addition, canine melanoma, due to its ...