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Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease
(Pergamon-Elsevier Science Ltd, 2001-01)
Brain-derived neurotrophic factor (BDNF) is a small dimeric protein, structurally related to nerve growth factor, which is abundantly and widely expressed in the adult mammalian brain. BDNF has been found to promote survival ...
Progesterone neuroprotection in spinal cord trauma involves up-regulation of brain-derived neurotrophic factor in motoneurons
(Pergamon-Elsevier Science Ltd, 2005-12)
Progesterone (PROG) provides neuroprotection to the injured central and peripheral nervous system. These effects may be due to regulation of myelin synthesis in glial cells and also to direct actions on neuronal function. ...
Aerobic exercise upregulates the BDNF-Serotonin systems and improves the cognitive function in rats
(Academic Press Inc Elsevier Science, 2018-11)
Aerobic exercise (AE) benefits brain health and behavior. Serotonin (5-HT) and brain-derived neurotrophic factor (BDNF) are known to mediate and shape cognitive processes. Both systems share some actions: BDNF is involved ...
Brain-Derived Neurotrophic Factor: A Key Molecule for Memory in the Healthy and the Pathological Brain
(Frontiers Media S.A., 2019-08)
Brain Derived Neurotrophic Factor (BDNF) is a key molecule involved in plastic changes related to learning and memory. The expression of BDNF is highly regulated, and can lead to great variability in BDNF levels in healthy ...
NMDA receptors contribute to the survival promoting effect of high potassium in cultured cerebellar granule cells
(Pergamon-Elsevier Science Ltd, 2005-10)
The present report further analyzes the survival promoting effect of high potassium, a condition that mimics neural activity in cultured cerebellar granule cells, an excellent model to study trophic mechanisms induced by ...
Brain derived neurotrophic factor and neurotrophin-4 employ different intracellular pathways to modulate norepinephrine uptake and release in rat hypothalamus
(Elsevier, 2009-08)
Classical actions of the neurotrophin family are related to cellular survival anddifferentiation. Moreover, acute effects of neurotrophins have been reported. Althoughneurotrophins effects on synaptic transmission at central ...
Brain-derived neurotrophic factor interacts with adult-born immature cells in the dentate gyrus during consolidation of overlapping memories
(Wiley, 2014-08)
Successful memory involves not only remembering information over time but also keeping memories distinct and less confusable. The computational process for making representations of similar input patterns more distinct ...
Brain-derived neurotrophic factor facilitates TrkB down-regulation and neuronal injury after status epilepticus in the rat hippocampus
(Wiley Blackwell Publishing, Inc, 2009-10-23)
Brain-derived neurotrophic factor (BDNF) is involved in many aspects of neuronal biology and hippocampal physiology. Status epilepticus (SE) is a condition in which prolonged seizures lead to neuronal degeneration. SE-induced ...
Pre-ischemic enriched environment increases retinal resilience to acute ischemic damage in adult rats
(Academic Press Ltd - Elsevier Science Ltd, 2019-01)
Retinal ischemia is a condition associated with several degenerative diseases leading to visual impairment and blindness worldwide. Currently, there is no highly effective therapy for ischemic retinopathies. This study was ...