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Synthesis and pharmacological properties of TOAC-labeled angiotensin and bradykinin analogs
(Elsevier B.V., 2002-01-01)
Angiotensin II (AngII) and bradykinin (BK) derivatives containing the TOAC (2,2,6,6-tetramethylpiperidine-N-oxyl-4-amino-4-carboxylic acid) spin label were synthesized by solid phase methodology. Ammonium hydroxide (pH 10, ...
Synthesis and pharmacological properties of TOAC-labeled angiotensin and bradykinin analogs
(Elsevier B.V., 2002-01-01)
Angiotensin II (AngII) and bradykinin (BK) derivatives containing the TOAC (2,2,6,6-tetramethylpiperidine-N-oxyl-4-amino-4-carboxylic acid) spin label were synthesized by solid phase methodology. Ammonium hydroxide (pH 10, ...
Synthesis and pharmacological properties of TOAC-labeled angiotensin and bradykinin analogs
(Elsevier B.V., 2002-01-01)
Angiotensin II (AngII) and bradykinin (BK) derivatives containing the TOAC (2,2,6,6-tetramethylpiperidine-N-oxyl-4-amino-4-carboxylic acid) spin label were synthesized by solid phase methodology. Ammonium hydroxide (pH 10, ...
BRADYKININ POTENTIATING and SENSITIZING ACTIVITIES of NEW SYNTHETIC ANALOGS of SNAKE-VENOM PEPTIDES
(Amer Chemical Soc, 1977-01-01)
Caracterização do sistema calicreína-cinina durante o processo ovulatório de bovinos
(Universidade Federal de Santa MariaBRMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina Veterinária, 2011-02-25)
The kallikrein-kinin system (KKS) has been described as an important mediator of physiologic processes. Kallikreins use kininogen (KNG) as substrate to generate bradykinin, the principal active peptide of the KKS which ...
Identification of a metallopeptidase with TOP-like activity in Paracoccidioides brasiliensis, with increased expression in a virulent strain
(Informa Healthcare, 2012-01-01)
Paracoccidioidomycosis (PCM), caused by the pathogenic fungus Paracoccidioides brasiliensis, is a systemic mycosis with severe acute and chronic forms. the pathology of PCM is not completely understood, and the role of ...
Cyclic, Linear, Cycloretro-Isomer, and Cycloretro-Inverso Peptides Derived from the C-Terminal Sequence of Bradykinin as Substrates or Inhibitors of Serine and Cysteine Proteases
(Springer, 2004-05-01)
We investigated the inhibition of trypsin, human tissue (hK1) and human plasma kallikrein (HuPK), papain, and cathepsin L, B, and X by synthetic cyclic, cycloretro-isomer, cycloretro-inverso, and linear peptides derived ...
Short peptide constructs mimic agonist sites of AT(1)R and BK receptors
(Springer, 2013-03-01)
Extracellular peptide ligand binding sites, which bind the N-termini of angiotensin II (AngII) and bradykinin (BK) peptides, are located on the N-terminal and extracellular loop 3 regions of the AT(1)R and BKRB1 or BKRB2 ...