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DNA Methylation-Based Method to Differentiate Malignant from Benign Thyroid Lesions
(Mary Ann Liebert, Inc, 2019-08-16)
Background: The differential diagnosis of thyroid nodules using fine-needle aspiration biopsy (FNAB) is challenging due to the inherent limitation of the cytology tests. The use of molecular markers has potential to ...
A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements
(Oxford University Press, 2004-02-01)
We report a method for studying global DNA methylation based on using bisulfite treatment of DNA and simultaneous PCR of multiple DNA repetitive elements, such as Alu elements and long interspersed nucleotide elements ...
A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements
(Oxford University Press, 2004-02-01)
We report a method for studying global DNA methylation based on using bisulfite treatment of DNA and simultaneous PCR of multiple DNA repetitive elements, such as Alu elements and long interspersed nucleotide elements ...
A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements
(Oxford University Press, 2014)
Comprehensive genome methylation and whole genome expression analysis in penile carcinoma: Uncovering new molecular markers
(Amer Assoc Cancer Research, 2014-10-01)
Background: Penile carcinoma (PeCa) is frequently associated with high morbidity rates. Unlikely of the vast majority of tumors, there is no molecular markers described that are able to assist in diagnosis and prognosis ...
Nonsyndromic orofacial clefts in Chile: LINE-1 methylation and MTHFR variants
(Future Medicine, 2020)
Aim: To evaluate the risk of nonsyndromic orofacial clefts (NSOFCs) associated with LINE-1 methylation, as a marker of global DNA methylation, and the effect of MTHFR functional variants on this variable. Patients & methods: ...
Nonsyndromic orofacial clefts in Chile: LINE-1 methylation and MTHFR variants
(2020)
Aim: To evaluate the risk of nonsyndromic orofacial clefts (NSOFCs) associated with LINE-1 methylation, as a marker of global DNA methylation, and the effect of MTHFR functional variants on this variable. Patients & methods: ...
Genetic and epigenetic effects in a population of underground miners with coal workers Pneumoconiosis
Coal Workers Pneumoconiosis (CWP) is a respiratory occupational disease caused by chronic exposure to breathable mine dust which is characterized by an inflammatory reaction and a subsequent progressive massive fibrosis. ...
E-Cadherin Downregulation is Mediated by Promoter Methylation in Canine Prostate Cancer
(2019-11-29)
E-cadherin is a transmembrane glycoprotein responsible for cell-to-cell adhesion, and its loss has been associated with metastasis development. Although E-cadherin downregulation was previously reported in canine prostate ...
Comprehensive analysis of DNA methylation and prediction of response to neoadjuvanttherapy in locally advanced rectal cancer
(2020-11-01)
The treatment for locally advanced rectal carcinomas (LARC) is based on neoadjuvant chemoradiotherapy (nCRT) and surgery, which results in pathological complete response (pCR) in up to 30% of patients. Since epigenetic ...