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Basal ganglia and functions of the autonomic nervous system
(Springer/Plenum Publishers, 2002-12)
The aim of this mini-review was to describe an underrecognized but important aspect of the basal ganglia diseases, the dysfunction of the autonomic nervous system that patients suffer owing to the degenerative process ...
Oscillations in the basal ganglia in Parkinson's disease: Role of the striatum
(Elsevier Gmbh, 2014-04)
In animal models of Parkinson´s disease cortical oscillations entrain abnormal synchronous rhythms in basal ganglia neurons. A mechanism accounting for these oscillations should: (i) vindicate a key role of the striatum ...
Alterations in time estimation in multiple system atrophy
(Elsevier, 2014-06)
Precise spatiotemporal performance is required by many common tasks and represents a basic aspect of cognition. Time estimation in the second-to-minutes range – known as interval timing – involves the interaction of the ...
Multiple-time-scale framework for understanding the progression of Parkinson's disease
(American Physical Society, 2014-12)
Parkinson's disease is marked by neurodegenerative processes that affect the pattern of discharge of basal ganglia neurons. The main features observed in the parkinsonian globus pallidus pars interna (GPi), a subdomain of ...
The indirect basal ganglia pathway in dopamine D2 receptor-deficient mice
(Pergamon-Elsevier Science Ltd, 2000-08)
Recent pathophysiological models of basal ganglia function in Parkinson's disease predict that specific neurochemical changes in the indirect pathway would follow the lack of stimulation of D2 dopamine receptors. Post ...
Structural neuroimaging differentiates vulnerability from disease manifestation in colombian families with Huntington's disease
(John Wiley & Sons Inc, 2019-07)
Introduction: The volume of the striatal structures has been associated with disease progression in individuals with Huntington's disease (HD) from North America, Europe, and Australia. However, it is not known whether the ...
Neuronal entropy depends on the level of alertness in the parkinsonian globus pallidus in vivo
(Frontiers, 2014-06)
A new working hypothesis of Parkinson's disease (PD) proposes to focus on the central role of entropy increase in the basal ganglia (BG) in movement disorders. The conditions necessary for entropy increase in vivo are, ...
Mechanisms for pattern specificity of deep-brain stimulation in Parkinson’s disease
(Public Library of Science, 2017-08-16)
Deep brain stimulation (DBS) has become a widely used technique for treating advanced stages of neurological and psychiatric illness. In the case of motor disorders related to basal ganglia (BG) dysfunction, several ...
Regional Heterogeneity of D2-Receptor Signaling in the Dorsal Striatum and Nucleus Accumbens
(Cell Press, 2018-05)
Dopamine input to the dorsal and ventral striatum originates from separate populations of midbrain neurons. Despite differences in afferent inputs and behavioral output, little is known about how dopamine release is encoded ...
Alterations in Metabolism and Diurnal Rhythms following Bilateral Surgical Removal of the Superior Cervical Ganglia in Rats
(Frontiers Media SA, 2018-01)
Mammalian circadian rhythms are controlled by a master pacemaker located in the suprachiasmatic nuclei (SCN), which is synchronized to the environment by photic and nonphotic stimuli. One of the main functions of the SCN ...