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Toxin-antitoxin systems and its biotechnological applications
(2014)
Toxin-antitoxin (TA) systems are important genetic modules composed by two elements: a toxin, that is always a protein, and an antitoxin, that can be a RNA or a protein and neutralizes the toxic effect of toxin. These ...
BtoxDB: a comprehensive database of protein structural data on toxin-antitoxin systems
(Elsevier B.V., 2015-03-01)
Purpose: Toxin-antitoxin (TA) systems are diverse and abundant genetic modules in prokaryotic cells that are typically formed by two genes encoding a stable toxin and a labile antitoxin. Because TA systems are able to ...
RalR (a DNase) and RalA (a small RNA) form a type I toxin-antitoxin system in Escherichia coli
(Oxford University Press, 2014-06)
For toxin/antitoxin (TA) systems, no toxin has been identified that functions by cleaving DNA. Here, we demonstrate that RalR and RalA of the cryptic prophage rac form a type I TA pair in which the antitoxin RNA is a ...
Kinetics of epsilon antitoxin antibodies in different strategies for active immunization of lambs against enterotoxaemia
(2013-10-14)
Enterotoxaemia, a common disease that affects domestic small ruminants, is mainly caused by the epsilon toxin of Clostridium perfringens type D. The present study tested four distinct immunization protocols to evaluate ...
Kinetics of epsilon antitoxin antibodies in different strategies for active immunization of lambs against enterotoxaemia
(2013-10-14)
Enterotoxaemia, a common disease that affects domestic small ruminants, is mainly caused by the epsilon toxin of Clostridium perfringens type D. The present study tested four distinct immunization protocols to evaluate ...
Toxin-antitoxin gene pairs found in Tn3 family transposons appear to be an integral part of the transposition module
(2020-03-01)
Much of the diversity of prokaryotic genomes is contributed by the tightly controlled recombination activity of transposons (Tns). The Tn3 family is argu-ably one of the most widespread transposon families. Members carry ...
Toxin-Antitoxin Gene Pairs Found in Tn3 Family Transposons Appear To Be an Integral Part of the Transposition Module
(Amer Soc Microbiology, 2020-03-01)
Much of the diversity of prokaryotic genomes is contributed by the tightly controlled recombination activity of transposons (Tns). The Tn3 family is arguably one of the most widespread transposon families. Members carry a ...