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OPG-Fc but Not Zoledronic Acid Discontinuation Reverses Osteonecrosis of the Jaws (ONJ) in Mice
(Wiley-Blackwell, 2015-09-01)
Osteonecrosis of the jaws (ONJ) is a significant complication of antiresorptive medications, such as bisphosphonates and denosumab. Antiresorptive discontinuation to promote healing of ONJ lesions remains highly controversial ...
Spontaneous osteonecrosis of the jaws in the maxilla of mice on antiresorptive treatment: A novel ONJ mouse model
(Elsevier B.V., 2014-11-01)
Although osteonecrosis of the jaws (ONJ), a serious complication of antiresorptive medications, was reported a decade ago, the exact mechanisms of disease pathophysiology remain elusive. ONJ-like lesions can be induced in ...
Successful use of lower-level laser therapy in the treatment of medication-related osteonecrosis of the jaw
(2017-09-01)
Case Presentation: This study aimed to report a case of medication related osteonecrosis of the jaw (MRONJ) of a 65-year-old female patient referred to the Oral and Maxillofacial Surgery team from Araçatuba Dental School, ...
Adjunctive application of antimicrobial photodynamic therapy in the prevention of medication-related osteonecrosis of the jaw following dentoalveolar surgery: A case series
(2019-09-01)
Background: Medication-related osteonecrosis of the jaw (MRONJ) is a debilitating complication strongly associated to antiresorptive agents. The present study aimed to describe the use of antimicrobial photodynamic therapy ...
Effect of antiresorptive drugs in the alveolar bone healing. A histometric and immunohistochemical study in ovariectomized rats
(2017-06-01)
Objectives: The aim of this study is to evaluate the alendronate and raloxifene influence in the alveolar healing process of osteoporotic rats. Materials and methods: Sixty-four female rats were divided in four groups: ...
Synchronous antiresorptive osteonecrosis of the jaws and breast cancer metastasis
(Elsevier Science IncNew YorkEUA, 2014)
Knowledge about osteoporosis in postmenopausal women undergoing antiresorptive treatment
(Elsevier Ireland LtdClareIrlanda, 2011)