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Diagnósticos e intervenções de enfermagem aos pacientes em terapia anticoagulante.
(2004-09-01)
Patients under treatment with oral anticoagulants present specific needs for which nursing care plays an important role, especially to prevent complications. The present review was carried out aiming at discussing nursing ...
Highlights from the I international symposium of thrombosis and anticoagulation in internal medicine, October 23-25, 2008, Sao Paulo, Brazil
(2009-04-08)
The importance of thrombosis and anticoagulation in clinical practice is rooted firmly in several fundamental constructs that can be applied both broadly and globally. Awareness and the appropriate use of anticoagulant ...
Significância clínica de tromboembolismo venoso recorrente
(2010-06-01)
Recurrent venous thromboembolism is a significant problem leading to increased morbidity and mortality. It has a high impact on patients' quality of life and imposes a great financial burden on society. Cumulative recurrence ...
Reversal of the anticoagulant and anti-hemostatic effect of low molecular weight heparin by direct prothrombin activation
(Associação Brasileira de Divulgação Científica (ABRADIC), 2012-10-01)
Lopap, found in the bristles of Lonomia obliqua caterpillar, is the first exogenous prothrombin activator that shows serine protease-like activity, independent of prothrombinase components and unique lipocalin reported to ...
Ultra-low-molecular-weight heparins: Precise structural features impacting specific anticoagulant activities
(Schattauer Gmbh-verlag Medizin Naturwissenschaften, 2013-03-01)
Ultra-low-molecular-weight heparins (ULMWHs) with better efficacy and safety ratios are under development; however, there are few structural data available. the main structural features and molecular weight of ULMWHs were ...
Intermolecular interactions and characterization of the novel factor Xa exosite involved in macromolecular recognition and inhibition: Crystal structure of human Gla-domainless factor Xa complexed with the anticoagulant protein NAPc2 from the hematophagous nematode Ancylostoma caninum
(Elsevier B.V., 2007-02-16)
NAPc2, an anticoagulant protein from the hematophagous nematode Ancylostoma caninum evaluated in phase-II/IIa clinical trials, inhibits the extrinsic blood coagulation pathway by a two step mechanism, initially interacting ...
Anticoagulant and antiprotease effects of a novel heparinlike compound from shrimp (Penaeus brasiliensis) and its neutralization by heparinase I
(Lippincott Williams & Wilkins, 2001-01-01)
Heparin is usually obtained from mammalian organs, such as beef lung, beef mucosa, porcine mucosa, and sheep intestinal mucosa. Because of the increased use of heparin in the production of low-molecular-weight heparin ...
Systematic review of randomized controlled trials of new anticoagulants for venous thromboembolism prophylaxis in major orthopedic surgeries, compared with enoxaparin
(2013-04-01)
Background: In the past 10 years, new anticoagulants (NACs) have been studied for venous thromboembolism (VTE) prophylaxis. Objective: To evaluate the risk/benefit profile of NACs versus enoxaparin for VTE prophylaxis in ...
PHARMACOLOGICAL and TOXICOLOGIC EFFECTS of 2 MAYTENUS SPECIES in LABORATORY-ANIMALS
(Elsevier B.V., 1991-08-01)
Leaves of Maytenus species are used in the popular medicine of Brazil for their reported antacid and antiulcerogenic activity. the present work examined the effects of a boiling water extract of equal parts of M. aquifolium ...