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Strategies to Optimize the Efficacy of Anthelmintic Drugs in Ruminants
(Elsevier, 2018-08)
Anthelmintic resistance in human and animal pathogenic helminths has been spreading in prevalence and severity. Multidrug resistance is a widespread problem in livestock animals. The use of available pharmacology-based ...
Basic and clinical pharmacology contribution to extend anthelmintic molecules lifespan
(Elsevier Science, 2015-08)
The correct use of pharmacology-based information is critical to design successful strategies for the future of parasite control in livestock animals. Integrated pharmaco-parasitological research approaches have greatly ...
Caenorhabditis elegans muscle Cys-loop receptors as novel targets of terpenoids with potential anthelmintic activity
(Public Library of Science, 2019-11)
The anthelmintic treatment of nematode infections remains the pillar of worm control in both human and veterinary medicine. Since control is threatened by the appearance of drug resistant nematodes, there is a need to ...
Anthelmintic resistance in cattle nematodes in northwestern São Paulo state, Brazil
(Elsevier B.V., 2007-09-30)
The present study was carried out in the northwestern region of São Paulo State, Brazil, to determine the anthelmintic resistance status in cattle naturally infected with gastrointestinal nematodes. The anthelmintics tested ...
Anthelmintic resistance in cattle nematodes in northwestern São Paulo state, Brazil
(Elsevier B.V., 2007-09-30)
The present study was carried out in the northwestern region of São Paulo State, Brazil, to determine the anthelmintic resistance status in cattle naturally infected with gastrointestinal nematodes. The anthelmintics tested ...
Host pharmacokinetics and drug accumulation of anthelmintics within target helminth parasites of ruminants
(New Zealand Veterinary Assoc Inc, 2017-07)
Anthelmintic drugs require effective concentrations to be attained at the site of parasite location for a certain period to assure their efficacy. The processes of absorption, distribution, metabolism and excretion ...
Anthelmintic therapy in ruminant species: Understanding of the host-drug-parasite interaction
(Bentham Science Publishers, 2010-05)
Inadequate use of anthelmitic drugs in livestock animals has led to therapeutic failures and to the dramatic widespread development of parasite resistance. Additional scientific knowledge on how to improve the use of ...
Anthelmintic resistance in grazing beef cattle in central and northeastern areas of Argentina — An update
(Elsevier Science, 2017-08)
The presence of anthelmintic resistance in Argentina has experienced a marked increase in cattle, with numerous reports showing levels of resistance of different parasite genera to different chemical groups. The aim of ...
Eficacy of ivermectin, moxidectin and febendazole in equine in Brazil
(2020-04-01)
The objectives of the present study were to evaluate the efficacy of three anthelmintic drugs, i.e. fenbendazole, ivermectin and moxidectin; to determine the genera and species of the most abundant strongyles; and to ...
Advances on metabolism and disposition of Bbnzimidazoles anthelmintic in Fasciola hepatica: its contribution to the phenomenon of anthelmintic resistance
(Springer, 2019)
The fascioliasis is an important zoonotic disease, particularly in underdeveloped countries. In fascioliasis, the anthelmintic control has been done mainly by the use of triclabendazole (TCBZ), which is metabolized into ...