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Caenorhabditis elegans muscle Cys-loop receptors as novel targets of terpenoids with potential anthelmintic activity
(Public Library of Science, 2019-11)
The anthelmintic treatment of nematode infections remains the pillar of worm control in both human and veterinary medicine. Since control is threatened by the appearance of drug resistant nematodes, there is a need to ...
Anthelmintic effect of Pterogyne nitens (Fabaceae) on eggs and larvae of Haemonchus contortus: Analyses of structure-activity relationships based on phenolic compounds
(2021-06-01)
Due to high prevalence and large pathogenicity, Haemonchus contortus is the main gastrointestinal nematode in tropical and subtropical regions. This species is responsible for severe economic losses to sheep and goat ...
Anthelmintic therapy in ruminant species: Understanding of the host-drug-parasite interaction
(Bentham Science Publishers, 2010-05)
Inadequate use of anthelmitic drugs in livestock animals has led to therapeutic failures and to the dramatic widespread development of parasite resistance. Additional scientific knowledge on how to improve the use of ...
Synthesis, Surface-Active Properties, and Anthelmintic Activities of New Cationic Gemini Surfactants Against the Gastrointestinal Nematode, Heligmosomoides polygyrus bakeri, In Vitro
(Springer Heidelberg, 2012-03)
A novel series of cationic dimeric surfactants was prepared involving the ketalization reaction, Williamson etherification, and regioselective oxirane ring opening with tertiary alkyl amines. The synthesized compounds were ...
Anticholinesterasic, Nematostatic and Anthelmintic Activities of Pyridinic and Pyrazinic Compounds
(Bentham Science Publ Ltd, 2011-08-01)
In the search for acetylcholinesterase inhibitors as a potential target for the discovery of anthelmintic drugs, a series of 27 pyridinic and pyrazinic compounds have been designed on the basis of molecular hybridization ...
Anticholinesterasic, Nematostatic and Anthelmintic Activities of Pyridinic and Pyrazinic Compounds
(Bentham Science Publ Ltd, 2011-08-01)
In the search for acetylcholinesterase inhibitors as a potential target for the discovery of anthelmintic drugs, a series of 27 pyridinic and pyrazinic compounds have been designed on the basis of molecular hybridization ...
A waterborn zoonotic helminthiase in an italian diver: a case report of a cutaneous sparganum infection and a review of european cases
(Taylor and Francis, 2016)
Many waterborne helminthes are opportunistic parasites that can travel directly from animals to man and may contain forms capable of penetrating the skin. Among these, Sparganum is the pseudophyllidean tapeworm that belongs ...