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Refining the intestinal motility test in mice to reduce animal stress
(2003-12-01)
A new protocol using 3-h fast animal for intestinal motility test was developed in our laboratory aiming the 3R's concept to reduce the stress of animals. Our results may aid in formulating recommendations that can be ...
Refining the intestinal motility test in mice to reduce animal stress
(2003-12-01)
A new protocol using 3-h fast animal for intestinal motility test was developed in our laboratory aiming the 3R's concept to reduce the stress of animals. Our results may aid in formulating recommendations that can be ...
Protocol to refine intestinal motility test in mice
(2004-07-01)
We propose a new protocol intended to conform to the 3Rs (replacement, reduction, and refinement) principle, using animals fasted for 3 h to control intestinal motility, which reduced stress in the animals. In this new ...
Protocol to refine intestinal motility test in mice
(2004-07-01)
We propose a new protocol intended to conform to the 3Rs (replacement, reduction, and refinement) principle, using animals fasted for 3 h to control intestinal motility, which reduced stress in the animals. In this new ...
Neurochemical, behavioral, and neurogenic validation of a hyposerotonergic animal model by voluntary oral consumption of PCPA
(American Chemical Society, 2020-02)
The inhibitor of tryptophan hydroxylase, para-chlorophenylalanine (PCPA), has been classically employed as a pharmacological tool to deplete serotonin (5-HT) in animal models and to evaluate whether this neurotransmitter ...
Characterization of a refinement of the "pylorus ligation" model of rat gastric ulceration resulting in "no pain" and a more specific pharmacological response
(Elsevier Science IncNew YorkEUA, 2013)