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Renin-angiotensin system blockers and severe acute respiratory syndrome coronavirus 2
Severe acute respiratory syndrome coronavirus 2, which is responsible for the current coronavirus
disease 2019 pandemic, uses angiotensin-converting enzyme 2 as a gateway into host cells. In this
review, we summarize the ...
Effect of hypertension on angiotensin-(1-7) levels in rats with different angiotensin-I converting enzyme polymorphism
(PERGAMON-ELSEVIER SCIENCE LTD, 2006)
To determine circulating angiotensin-(1-7) [Ang-(1,7)] levels in rats with different angiotensin converting enzyme (ACE) genotypes and to evaluate the effect of hypertension on levels of this heptapeptide, plasma levels ...
Angiotensin I-converting enzyme insertion/delection polymorphism and adrenergic response to exercise in hypertensive patients
(International Medical Science for Experimental and Clinical Research, 2002)
The insertion/delection ACE polymorphism (ACE I/D) regulates different levels of circulating and tissue ACE activities, which may induce diverse adrenergic responses to physiological stimuli. The aim of this study was ...
New mass spectrometric assay for angiotensin-converting enzyme 2 activity
(Lippincott Williams & WilkinsPhiladelphiaEUA, 2006)
PINDOLOL Df,CREASES PLASMA ANGIOTENSIN-CONVERTING ENZYME ACTIVITY IN YOUNG SPONTANEOUSLY HYPERTTNSIVE RATS
(European Journal ol Pharmocolog/,, 2011)
ACE2-angiotensin-(1-7)-Mas axis in renal ischaemia/reperfusion injury in rats
(Portland Press Ltd, 2010-11-01)
AngII (angiotensin II), ACE (angiotensin I-converting enzyme) and the AT(1) receptor (AngII type I receptor) are associated with the inflammatory process and microvascular dysfunction of AKI (acute kidney injury) induced ...
Prevalence of the angiotensin I converting enzyme insertion deletion polymorphism, plasma angiotensin converting enzyme activity, and left ventricular mass in a normotensive Chilean population
(ELSEVIER SCIENCE INC, 1999)
The aim of this study was to estimate the prevalence of the different alleles of the angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and associated plasma ACE activity, as well as cardiac ...
Alternative pathways for angiotensin II generation in the cardiovascular system
(Associação Brasileira de Divulgação Científica, 2011)
The classical renin-angiotensin system (RAS) consists of enzymes and peptides that regulate blood pressure and electrolyte and fluid homeostasis. Angiotensin II (Ang II) is one of the most important and extensively studied ...
Angiotensin I-converting enzyme modulates neutral endopeptidase activity in the rat
(LIPPINCOTT WILLIAMS & WILKINS, 2001-09)
Angiotensin I is a substrate for both ACE and for neutral endopeptidase 24.11 (NEP). We hypothesized that high ACE expression is related to low NEP activity. Accordingly, circulating and tissue NEP and ACE activities were ...
Angiotensin converting enzyme polymorphism in type 2 diabetes mellitus
(2014)
This study was undertaken to assess the frequency of angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism in patients with type 2 diabetes mellitus. A total of 162 patients with type 2 diabetes and 160 ...